Results 151 to 160 of about 275,467 (315)

Construction Machines as a Source of Construction noise

open access: yesProcedia Engineering, 2017
Abstract The contribution deals with issues concerning the modelling of the production area of a construction site from the aspect of the placement of construction machines, which are a source of noise for the protected area outside the site according to Government Regulation No. 272/2011 Coll. It covers the determination of a construction site noise
openaire   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Constructions and context: when a construction constructs context

open access: yes, 2009
The aim of the paper is to address a case of a syntactic pattern involving context, which can be summed up by this assumption : a construction provides pieces of context that the speaker considers to be necessary for the addressee to get a relevant interpretation of the current utterance.
Deulofeu, Jose, Debaisieux, Jeanne-Marie
openaire   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Research of Temperature and Moisture during Sitting on Office Chairs

open access: yesDrvna Industrija, 2012
When using an office chair, a person comes into direct contact with the seat, where the contact surface creates a microclimate that affects the person’s positive or negative mood, depending on temperature and humidity.
Zoran Vlaović   +2 more
doaj  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Papers on predicative constructions : Proceedings of the workshop on secundary predication, October 16-17, 2000, Berlin

open access: yes, 2001
This volume presents a collection of papers touching on various issues concerning the syntax and semantics of predicative constructions. A hot topic in the study of predicative copula constructions, with direct implications for the treatment of he (how ...
Strigin, Anatolij   +3 more
core  

Towards a lexically specific grammar of children’s question constructions

open access: yes, 2005
This paper examines early syntactic development from a usage-based perspective, using transcripts of the spontaneous speech of two English-speaking children recorded at relatively dense intervals at ages 2;0 and 3;0.
Lieven, Elena   +3 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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