Results 81 to 90 of about 77,261 (266)

Optimal constructions

open access: yes, 2016
This paper deals with a well-known problem in the discussion of argument linking, the flexibility that we find with particular verbs, and the constraints governing the integration of verbs with so-called argument structure constructions. We will show that traditional approaches as well as construction grammar need additional machinery to deal with ...
Vogel, Ralf   +4 more
openaire   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Emerging Constructions in the L2 Italian Spoken by Low Literate Migrants

open access: yesLanguages, 2019
The emergence of autonomous interlanguage constructions is widely recognised in the literature on L2 Italian. These constructions involve the overgeneralisation of functional forms learners are in the process of acquiring, e.g., siamo in siamo mangiare &#
Egle Mocciaro
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Study on the concentrations of inorganic compounds in office spaces [PDF]

open access: yesConstructii: Journal of Civil Engineering Research, 2014
Indoor environment affects equally the health, the productivity and the occupants comfort, the costs for employers, owners of the buildings and the society being significantly larger, in the case of an inadequate interior ambient.
Alina DIMA, Vasilica VASILE, Mihaela ION
doaj  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Sõnavara ja konstruktsioonide areng eesti keelt teise keelena omandava noore õppija kõnes aasta jooksul

open access: yesEesti Rakenduslingvistika Ühingu Aastaraamat
Artiklis vaadeldakse eesti keelt teise keelena omandavate 8–10-aastaste laste sõnavara ja konstruktsioonide arengut aasta jooksul 2022. ja 2023. aastal läbi viidud pildikirjelduskatse põhjal.
Reili Argus, Tiina Rüütmaa
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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