Results 81 to 90 of about 79,708 (267)

From location to conjunction, disjunction, partition, exemplification and association: Hebrew bein constructions

open access: yesLinguistics
Analyzing the diachrony of Hebrew bein, originally a spatial preposition ‘within/among’, this article traces several grammaticization clines associated with bein’s gradual evolution into a rich variety of functions within various constructions. While its
Bardenstein Ruti, Ariel Mira
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Early‐Phase Research in Pediatric Neuro‐Oncology

open access: yes
Pediatric Blood &Cancer, EarlyView.
Jonathan Cunningham
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

THE DEVELOPMENT OF THE INNOVATION NANO COMPOSITE MATERIAL FOR UNMANNED AIRCRAFT VEHICLES

open access: yesСовременная наука и инновации, 2022
This paper presents the investigations of innovation nanocomposite material to increase structural strength, reduce weight and provide radio transparency in unmanned aircraft vehicles.
Galina Mikhaylovna Danilova-Volkovskaya   +1 more
doaj  

Grammaticalisation et acquisition des constructions causatives en français et en bulgare

open access: yesCogniTextes, 2010
This article is in two parts. In the first part, we are concerned with the diachronic evolution of causative constructions in French and Bulgarian. In French, the change goes from periphrastic forms V1 causative + NP + V2 inf in Latin to the complex ...
Yanka Bezinska, Iva Novakova
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Polish in the light of grammaticalization theory

open access: yesCognitive Studies | Études cognitives, 2015
Polish in the light of grammaticalization theory The paper is concerned with grammaticalization, a type of language change whereby lexical items, in specifi contexts, come to serve grammatical functions, and grammatical items acquire new grammatical ...
Björn Hansen, Ana Drobnjaković
doaj   +1 more source

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