Results 81 to 90 of about 275,467 (315)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Verbo-Nominal Constructions withkommen‘come’ in German

open access: yes, 2022
The paper presents the results of a diachronic study of the light verb constructions containing the German verbkommen‘come’ accompanied by a prepositional phrase containing a deverbal noun and the prepositionzu‘to’.
Elena Smirnova   +2 more
core   +1 more source

Emerging Constructions in the L2 Italian Spoken by Low Literate Migrants

open access: yesLanguages, 2019
The emergence of autonomous interlanguage constructions is widely recognised in the literature on L2 Italian. These constructions involve the overgeneralisation of functional forms learners are in the process of acquiring, e.g., siamo in siamo mangiare &#
Egle Mocciaro
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

ACCOUNTING AND FISCAL ASPECTS RELATED TO CONSTRUCTIONS AND LAND [PDF]

open access: yesBuletin ştiinţific: Universitatea din Piteşti. Seria Ştiinţe Economice, 2021
This paper approaches aspects related to the value added tax in the case of operations with real property. The presentation of the theoretical notions and the applications are grouped on types of operations: exempt from VAT; voluntarily liable to pay VAT,
Marcela BENGESCU
doaj  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Study on the concentrations of inorganic compounds in office spaces [PDF]

open access: yesConstructii: Journal of Civil Engineering Research, 2014
Indoor environment affects equally the health, the productivity and the occupants comfort, the costs for employers, owners of the buildings and the society being significantly larger, in the case of an inadequate interior ambient.
Alina DIMA, Vasilica VASILE, Mihaela ION
doaj  

Compositionnalité gestaltiste et construction du sens par instructions dynamiques

open access: yesCogniTextes, 2010
The pervasiveness of polysemy in languages compels us to consider the interpretation of utterances as a dynamic process in which the meaning of each linguistic unit is determined as the overall meaning of the utterance is constructed.
Gilles Col   +3 more
doaj   +1 more source

On a construction of schützenberger

open access: yesDiscrete Mathematics, 1977
Schiitzenberger's construction is a construction involving Young tableaux and may be found in either of the two works [2] and [3] by Schiitzenberger. It is described in these works as an operator which acts on the numbers appearing in a Young tableau. In a lecture at the Permutations Colloquium in Paris in July 1972, however, Schiitzenberger described ...
openaire   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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