Results 91 to 100 of about 9,754,066 (286)

Human Foetal Neuroblasts Exhibit BK Channel‐Dependent Membrane Voltage Oscillations upon Depolarization

Advanced Science, EarlyView.
Primary cultures of neuroblasts isolated from the nucleus basalis of Meynert of 12‐weeks‐old human foetuses were prepared. Whole‐cell patch‐clamp recordings were performed by injecting a depolarizing stimulus current (+500 pA; 500 ms), and the membrane voltage recorded; this stimulus current evoked periodic‐like oscillations in membrane voltage ...
Elisabetta Coppi, Federica Cherchi, Martina Venturini, Federico Tommasi, Sandro Gonzi, Chiara Capacci, Giulia Guarnieri, Pasquale Gallina, Annamaria Morelli, Anna Maria Pugliese   +9 more
wiley   +1 more source

Understanding how advanced parametric design can improve the constructability of building designs

, 2016
Construction project complexity is rapidly growing, increasing the need for better project and design management practices. This complexity is attributable to the advancements in technology which have resulted in an intensification of contemporary design generation.
openaire   +1 more source

Phonon‐Driven Tetrahedral Tilts Enable Ultralow Bulk Thermal Expansion and Interstitial Oxide‐Ion Migration in Phenacite Solid Electrolytes

Advanced Science, EarlyView.
This work demonstrates a design paradigm of phonon‐driven negative‐thermal‐expansion (NTE) flexible framework that exploits the intrinsic lattice flexibility of NTE frameworks to simultaneously suppress thermal expansion and activate oxide‐ion conduction, offering a promising strategy to mitigate TEC mismatch in solid‐state ionic devices.
Xiaohui Li, Lu liang, Qilong Shi, Xiaoge Wang, Cheng Li, Sihao Deng, Lunhua He, Qiang Li, Kun Lin, Xianran Xing, Xiaojun Kuang   +10 more
wiley   +1 more source

A Schema for Capturing and Comparing Parametric Spatial Data

, 2013
In this paper, the authors consider the problem of architectural spatial performance indicators for assessing computer generated design, where identification and analysis of meaningful and relevant spatial qualities is the target of assessment. The paper
Coorey, BP, B.P. Coorey, J.R. Jupp, Jupp, JR   +3 more
core  

A Personalized Haplotype‐Resolved Near‐Gapless Genome Framework for Somatic Variant Discovery in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A patient‐specific, haplotype‐resolved genome framework improves detection and interpretation of somatic variants in hepatocellular carcinoma. Using multi‐platform sequencing, the personalized assembly resolves complex regions including centromeres and MHC/HLA loci, enhances structural variant discovery, and links regulatory alterations to allele ...
Jiazheng Lin, Yao Xiao, Shuangzi Luo, Yifan Li, Wenfei Zhang, Xiaoyu Zhang, Xinyi Wang, Di Wu, Jieru Hong, Yongkun Luan, Xun Huang, Yixiu Wang, Ningbo Wu, Xiaoxiao Hu, Fei Zhao, Wei Li, Xiao Luo, Bi Shi   +17 more
wiley   +1 more source

Parametric modelling and design processes: Exploringsynthesis and evaluation using a Function-Behaviour-Structure perspective [PDF]

, 2011
In an attempt to extend our understanding of the design process in the context of computational parametric design tools, this paper explores the relationship between and interaction of synthesis and evaluation.
B. Coorey, Corey, BP, J. Jupp, Jupp, JR
core  

B Cells are Activated via a Nanoporous Interface that Stabilizes Microvilli and Engages Mechanosensitive Ion Channels

Advanced Science, EarlyView.
B cells can be activated independently of antigen recognition via mechanical stimulation through nanoporous substrates. Exposure to such substrates induced B cell microvilli extension into the pores, intracellular Ca2+ signaling, phosphorylation of signaling proteins, and CD69 expression.
Nozie D. Aghaizu, Willi Weber, Nadine Strempel, Asya Polat, Enrico Klotzsch   +4 more
wiley   +1 more source

Parametric Design in Architecture Education

, 2021
Advancements in digital technologies have affected architecture education as well. In this direction, in order to prepare the students for the occupational environment, alterations have been made in architecture education program as well and lectures ...
Varli E.
core   +1 more source

Dimple‐Encoded Reprogrammable Origami

Advanced Science, EarlyView.
Local snap‐through of bistable dimples turns flat elastic sheets into reprogrammable origami structures. Interaction‐guided dimple arrays act as angle‐programmable hinge bands, enabling one sheet to morph into distinct polygonal and three‐dimensional configurations while retaining stable shapes for deployable and protective functions.
Qun Zhang, Weicheng Huang, Amir Hajiyavand, Hyunyoung Kim, Claire Dancer, Karl Dearn, Mingchao Liu   +6 more
wiley   +1 more source

Economic Uncertainty Assessment Using a Combined Design of Experiments/Monte Carlo Simulation Approach with Application to an HSCT

, 1995
Presented at the 17th Annual Conference of the International Society of Parametric Analysts, San Diego, CA, May, 1995.Recently, the aerospace industry has felt the impact of the combined effect of increasing aircraft systems costs and budget restrictions
Bandte, Oliver, Mavris, Dimitri N.
core