Results 91 to 100 of about 808,049 (434)

Polyfunctional CD8+CD226+RUNX2hi effector T cells are diminished in advanced stages of chronic lymphocytic leukemia

open access: yesMolecular Oncology, Volume 19, Issue 5, Page 1347-1370, May 2025.
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar   +4 more
wiley   +1 more source

A novel approach to in-depth façade assessments: Improved corrosion test methods for embedded steel framing in historic masonry clad buildings [PDF]

open access: yesMATEC Web of Conferences, 2019
Corrosion of structural steel frames and associated steel assemblies within ‘vintage’ buildings circa 1880s to 1930s pose a health and safety risk to the public in major urban centers.
Crevello Gina   +2 more
doaj   +1 more source

White Paper: Brief overview of current practices for open consultation [PDF]

open access: yesarXiv, 2016
The purpose of this document is to provide a brief overview of open consultation approaches in the current, international setting and propose a role for Information Technologies (IT) as a disruptive force in this setting.
arxiv  

Consultation Checklists: Standardising the Human Evaluation of Medical Note Generation [PDF]

open access: yesarXiv, 2022
Evaluating automatically generated text is generally hard due to the inherently subjective nature of many aspects of the output quality. This difficulty is compounded in automatic consultation note generation by differing opinions between medical experts both about which patient statements should be included in generated notes and about their ...
arxiv  

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

Strategic Consulting in the Region

open access: yesУправленческое консультирование, 2019
The article is devoted to the procedures of organizing group work in the process of forming the main content of the development strategy of the modern Russian region in accordance with the current legislation, which, however, does not have ...
Yu. N. Lapygin   +2 more
doaj   +1 more source

Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐CD73/anti‐PD‐L1 immunotherapy in arm A of the NSGO‐OV‐UMB1/ENGOT‐OV30 trial

open access: yesMolecular Oncology, Volume 19, Issue 5, Page 1436-1451, May 2025.
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric   +11 more
wiley   +1 more source

What is the impact of labor displacement on management consulting services? [PDF]

open access: yesarXiv, 2020
Labor displacement off-or nearshore is a performance improvement instrument that currently sparks a lot of interest in the service sector. This article proposes a model to understand the consequences of such a decision on management consulting firms. Its calibration on the market of consulting services for the German transportation industry highlights ...
arxiv  

PUCM 2 Survey Results 2001-2002 [PDF]

open access: yes, 2002
This Report contains the results from a survey of resource management consultants and resource consent applicants carried out during 2001-2002 to gain factual and attitudinal information about the plan implementation processes of respective councils. It
Backhurst, Michael, Day, Maxine
core   +1 more source

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

open access: yesMolecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen   +17 more
wiley   +1 more source

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