Results 61 to 70 of about 835,238 (391)
Tocilizumab as a Therapeutic Agent for Critically Ill Patients Infected with SARS‐CoV‐2
Clinical and Translational Science, 2021 Tocilizumab is an IL‐6 receptor antagonist with the ability to suppress the cytokine storm in critically ill patients infected with severe acute respiratory syndrome‐coronavirus 2 (SARS‐CoV‐2).
Russell M. Petrak +25 more
doaj +1 more source
Vietnam Journal of Computer Science, 2015 The hierarchical organisation of distributed systems can provide an efficient decomposition for machine learning. This paper proposes an algorithm for cooperative policy construction for independent learners, named Q-learning with aggregation (QA ...
Bilal H. Abed-alguni +3 more
semanticscholar +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Consultants and firm-level innovation performances: a doubly robust estimation approach [PDF]
Eastern Journal of European Studies, 2020 This paper examines firms use of external consultants and commercial labs as an essential source of knowledge for innovation performance and activities in the IT and other information service firms.
Samuel AMPONSAH ODEI +2 more
doaj
International Journal of Retina and Vitreous, 2020 Background To evaluate visual and safety outcomes for 25-gauge (25G) and 27-gauge (27G) micro-incision vitrectomy platforms (MIVS) for the treatment of epiretinal membrane and full-thickness macular holes.
Gordon T. Brown +5 more
doaj +1 more source
Drugs - Real World Outcomes, 2022 Background The coronavirus disease 2019 (COVID-19) pandemic has led to disruptions of healthcare delivery and may thus have impacted patterns of prescription opioid use, including risk factors for long-term use.
Anne-Marie Castilloux +2 more
doaj +1 more source
Optimizing patient referrals to dental consultants: Implication of teledentistry in rural settings
, 2016 The uneven distribution of dental practitioners (particularly consultants – in Australia commonly called specialists) in Australia creates a barrier to accessing consultant level dental care. This maldistribution often results in the isolation of general
M. Estai, E. Kruger, M. Tennant
semanticscholar +1 more source
Quality and Safety in Health Care, 2004 Exploring the use of game theory to address quality Game theory and clinical practice seem an unlikely marriage and it may not be obvious how such a combination could improve the quality of clinical consultations. But this area of applied mathematics seems set to reduce some of our quintessential human foibles to a predictable set of behaviours based ...
openaire +4 more sources
Molecular Oncology, EarlyView.In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source