Results 81 to 90 of about 661,800 (294)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Factors impeding the industrialized building system (IBS) implementation of building construction in Malaysia [PDF]

open access: yes, 2018
In Malaysian construction industry, Industrialised Building System (IBS) has been introduced to replace the traditional construction method. While the government has been making significant efforts to encourage the IBS adoption, the uptake of IBS in ...
Abas, Nor Ain   +3 more
core   +1 more source

Consulting Relatives

open access: yesThe Bulletin of the Royal College of Surgeons of England, 2016
Each month we take a close look at a recent legal case with implications for the surgical profession.
openaire   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

The Exploitation of Potential Immigrants by Unscrupulous Consultants: A Task Force Report

open access: yesRefuge, 1982
In 1981, 1047 claims for refugee status were filed by Indian nationals. Of the 400 that have been considered none have been accepted. "Unscrupulous travel agents", it seems, swindled hundreds of would-be immigrants, sometimes out of everything ...
A. Duff Mitchell
doaj   +1 more source

Resource Directory for Nonprofit Capacity Building in California's Central Valley [PDF]

open access: yes, 2006
Provides an overview of recent studies of Central Valley's nonprofit sector, and a list of consultants, foundations, community organizations, and other institutions that provide capacity building services and resources to nonprofit ...

core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Defining Hierarchical Decision Trees for Encarsia Formosa Strategies from Greenhouse Tomato Consultants' Perspectives [PDF]

open access: yes
Market pressure is forcing New Zealand greenhouse tomato growers to shift from conventional to more environmentally-friendly pest control methods such as IPM (Integrated Pest Management).
Cameron, Ewen   +2 more
core   +1 more source

Memorandum on The Use of Struksnes Polls to Test Majority Status, 1979 [PDF]

open access: yes, 1979
Memo to all consultants, presenting the ways an employer is able to determine a union\u27s majority status.
Ogden, Warren C
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

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