Results 41 to 50 of about 536,092 (268)
Scientific ReportsIllness perceptions (IP), as measured by the Brief Illness Perception Questionnaire (BIPQ), and adverse childhood experiences (ACE) have been shown to affect the physical and psychological well-being in different patient populations.
Marc Dörner +11 more
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Consultant – not sub-consultant [PDF]
The Bulletin of the Royal College of Surgeons of England, 2006 This College's position on the end point of training and the award of a Certificate of Completion of Training (CCT) continues to provoke comment. A report in Hospital Doctor in April 2006 quotes a trainee representative calling into question my personal position vis-à-vis the creation of a sub-consultant grade, while Hospital Doctor in its same report
openaire +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Scientific ReportsPatients with implantable cardioverter-defibrillators (ICDs) are vulnerable to psychological distress, including posttraumatic stress disorder (PTSD). Impaired sleep is a hallmark of PTSD, and may also act as a risk factor that maintains or exacerbates ...
Ladina Nager +11 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Développement Durable et Territoires, 2006 Since the 90’s in the French region watered by the river Charente water resources have been weighed down with irrigation. In order to reduce conflicts which are linked to this situation, «Volumetric Management » introduces some new rules for irrigation ...
Céline Granjou, Patrice Garin
doaj +1 more source
Clinical Medicine, 2001 La biographie du Docteur Christian Munch est decrite a travers l'art, particulierement sa vie tourmentee par la mort de sa femme et son mal ...
openaire +10 more sources
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
PCN Reports, 2022 Aim Previous research shows that telephone consultation is useful in suicide prevention, substance use disorder, and other mental illnesses. However, no study has been conducted with a specific focus on telephone consultation for patients with bipolar ...
Yuko Isogaya +4 more
doaj +1 more source