Results 61 to 70 of about 522,473 (266)

A consultation and work-up diagnosis protocol for a multicancer early detection test: a case series study

open access: yesFuture Science OA
The emergence of multicancer early detection (MCED) tests holds promise for improving early cancer detection and public health outcomes. However, positive MCED test results require confirmation through recommended cancer diagnostic imaging modalities. To
Luu Hong Dang Nguyen   +50 more
doaj   +1 more source

Even if they are not aware of it, general practitioners improve well-being in their adolescent patients

open access: yesEuropean Journal of General Practice, 2017
Background: Most adolescents consult their general practitioner (GP) for common reasons, somatic or administrative but many of them have hidden feelings of distress.
Benoit V. Tudrej   +5 more
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

A Multidisciplinary Analysis of Adults Referred for Psychiatric Consultation in the Emergency Department: Clinical Insights from a Period of Over One Year on Demographic Characteristics and Outcomes

open access: yesGlobal Emergency and Critical Care
Objective: Emergency departments (EDs) frequently encounter patients experiencing mental health (MH) crises, which significantly affect healthcare systems.
Meltem Gürü, Süeda Zaman
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

FREE, PRIOR AND INFORMED CONSENT (FPIC) IN MEXICO: ELEMENTS FOR ITS CONSTRUCTION AND CHALLENGES

open access: yesAge of Human Rights Journal, 2019
Free, Prior and Informed Consent (FPIC) - Consultation has become one of the most powerful tools indigenous people and minorities have to generate a dialogue and begin a negotiation in the country to face Government decisions, private companies seeking ...
JOSE ISRAEL HERRERA
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Relationship Between Family Power Structure, Marital Conflicts, and Mental Health in Male Retirees of Alborz Province Department, Iran Ministry of Education

open access: yesSālmand, 2016
Objectives: Purpose of this study was to analyze the relationship and effects of family power structure, marital conflicts, and their components on mental health in male retirees of education in Alborz Province.
Maryam Soleimani   +3 more
doaj  

Research on the implementation and effectiveness evaluation of deep reinforcement learning algorithms for portfolio optimisation

open access: yesDiscover Artificial Intelligence
Portfolio optimisation is the process of continuously allocating money to different assets to maximize returns, and since the theory was introduced in 1952, many researchers have improved upon it by introducing constraints and other objectives to make ...
Gao Yunxiang, Tang Bangying
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

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