Results 71 to 80 of about 1,839,265 (292)

Network Localization of Fatigue in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo, Jaakko Kungshamn, Albert Bellmunt‐Gil, Silvia Tommasin, Abhineet Ojha, Matias Viitala, Juho Aaltonen, Jyrki Lötjönen, Juha Koikkalainen, Pauli Ylikotila, Patrizia Pantano, Merja Soilu‐Hänninen, Juho Joutsa   +12 more
wiley   +1 more source

FREE, PRIOR AND INFORMED CONSENT (FPIC) IN MEXICO: ELEMENTS FOR ITS CONSTRUCTION AND CHALLENGES

Age of Human Rights Journal, 2019
Free, Prior and Informed Consent (FPIC) - Consultation has become one of the most powerful tools indigenous people and minorities have to generate a dialogue and begin a negotiation in the country to face Government decisions, private companies seeking ...
JOSE ISRAEL HERRERA
doaj   +1 more source

Industry use of evidence to influence alcohol policy: a case study of submissions to the 2008 Scottish government consultation. [PDF]

, 2013
Jim McCambridge and colleagues analyze industry submissions to a Scottish Government consultation on whole-population approaches to alcohol ...
Hawkins, Ben, Holden, Chris, McCambridge, Jim   +2 more
core   +2 more sources

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Relationship Between Family Power Structure, Marital Conflicts, and Mental Health in Male Retirees of Alborz Province Department, Iran Ministry of Education

Sālmand, 2016
Objectives: Purpose of this study was to analyze the relationship and effects of family power structure, marital conflicts, and their components on mental health in male retirees of education in Alborz Province.
Maryam Soleimani, Soraya Azimian, Ali Mohammad Nazari, Kiyanosh Zahrakar   +3 more
doaj  

Research on the implementation and effectiveness evaluation of deep reinforcement learning algorithms for portfolio optimisation

Discover Artificial Intelligence
Portfolio optimisation is the process of continuously allocating money to different assets to maximize returns, and since the theory was introduced in 1952, many researchers have improved upon it by introducing constraints and other objectives to make ...
Gao Yunxiang, Tang Bangying
doaj   +1 more source

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer, Frauke Stascheit, Maximilian Mönch, Paolo Doksani, Carla Dusemund, Meret Herdick, Philipp Mergenthaler, Maike Stein, Amani Suboh, Jutta Schröder‐Braunstein, Guido Wabnitz, Jan D. Lünemann, Sophie Lehnerer, Sarah Hoffmann, Andreas Meisel   +14 more
wiley   +1 more source

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source

Changes in the Death Status of End-of-life Patients After Concept Promotion and Practice of Palliative Care

Xiehe Yixue Zazhi
Objective  The International Medical Services Department of Peking Union Medical College Hospital (PUMCH) has gradually promoted the concept and practice of palliative care since 2016.
DAI Xiaoyan, YAN Jing, WANG Youpei, NING Xiaohong   +3 more
doaj   +1 more source

Response to the DECC Consultation of the siting process for a Geological Disposal Facility, 2013 [PDF]

, 2013
Several members of SEG (Matt Gross, Phil Johnstone, Florian Kern, Gordon MacKerron, and Andy Stirling) have participated in a written response to the Department of Energy and Climate Change’s (DECC) consultation of the siting process for a Geological ...
Gross, Matthew, Johnstone, Philip, Kern, Florian, MacKerron, Gordon, Stirling, Andrew   +4 more
core