Results 41 to 50 of about 83,766 (257)
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Austrian Journal of Statistics, 2016 In this paper, double acceptance sampling plans are developed for a truncated life test, when the lifetime of an item follows the Marshall-Olkin extended exponential distribution.
G. Srinivasa Rao
doaj +1 more source
Scaling of the risk landscape drives optimal life history strategies and the evolution of grazing [PDF]
, 2019 Consumers face numerous risks that can be minimized by incorporating different life-history strategies. How much and when a consumer adds to its energetic reserves or invests in reproduction are key behavioral and physiological adaptations that structure
Bhat, Uttam +2 more
core +3 more sources
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Impossibility of Differentially Private Universally Optimal Mechanisms
, 2010 The notion of a universally utility-maximizing privacy mechanism was recently introduced by Ghosh, Roughgarden, and Sundararajan [STOC 2009]. These are mechanisms that guarantee optimal utility to a large class of information consumers, simultaneously ...
Brenner, Hai, Nissim, Kobbi
core +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Designing of multiple dependent state sampling plan for Exponentiated Frechet Distribution
Research in StatisticsAn approach for making decisions regarding the lot being inspected is acceptance sampling. A decision regarding the entire lot under inspection is made based on a representative sample.
Gadde Srinivasa Rao +2 more
doaj +1 more source
Generalized Multiple Dependent State Sampling Plans in Presence of Measurement Data
IEEE Access, 2020 This article introduces a generalized version of the multiple dependent state sampling plan based on the measurement data, that is, when the quality characteristic is measured in a numerical scale.
Ritwik Bhattacharya, Muhammad Aslam
doaj +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source