Dynamic Single‐Binding Event Profiling With on‐Chip Microlenses for Wash‐Free Digital Biosensing
A microlens‐enhanced platform enables real‐time tracking and digital counting of single‐binding events using conventional bright‐field microscopy. Amplified scattering signals from gold nanoparticle labels and kinetic signature analysis allow wash‐free discrimination between specific and nonspecific interactions, while providing kinetic and mechanistic
Tingting Zhan +12 more
wiley +1 more source
Impact of Functional Feed Additives and Lower Antibiotic Use on Poultry Meat Quality and Consumer Perception. [PDF]
Samad A +7 more
europepmc +1 more source
Adipocyte Myoglobin Is a Determinant of Energy Expenditure and a Potential Target to Limit Obesity
Myoglobin, known as a muscle oxygen‐carrying protein, is shown to play a key role in fat cells that burn energy. Loss of myoglobin reduces the body's ability to generate heat and increases obesity risk, while restoring it improves metabolism. The study identifies myoglobin as a regulator of fat burning and a potential target to enhance energy ...
Christian Strehlau +22 more
wiley +1 more source
A Clinical Quality-Assurance Panel for Patient-Facing Black-Box Large Language Models in Healthcare: Anchored Forced-Choice Drift Monitoring for Sensitive Communication. [PDF]
Harada Y.
europepmc +1 more source
Tumor‐derived GDF15 drives cancer cachexia and suppresses antitumor immunity. Here, de novo designed minibinders targeting the GDF15–GFRAL interface achieve picomolar affinity and potent pathway blockade. The minibinders alleviate cachexia, restore CD8+ T‐cell infiltration, enhance anti–PD‐1 responsiveness, and provide survival benefits across tumor ...
Haitao Wang +8 more
wiley +1 more source
No Loan Comes Without a Price: Financial Literacy, Mental Health, and Consumer Loan Use Among Young Adults in Sweden. [PDF]
Levinsson H +3 more
europepmc +1 more source
Polarization Dynamics in Ferroelectrics: Insights Enabled by Machine Learning Molecular Dynamics
Machine learning molecular dynamics is presented as a route to capture polarization switching, domain wall kinetics, topological polar textures, and polar mechanical coupling beyond the limits of conventional atomistic methods. This Perspective surveys recent progress and identifies key methodological directions, including long‐range electrostatics ...
Dongyu Bai +3 more
wiley +1 more source
Linking Sustainable Smart Food Packaging to Healthy Eating Behaviors: A TPB-Perceived Value Framework with IPMA Analysis. [PDF]
Mu J, Zhou L, Yang C.
europepmc +1 more source
Artificial Intelligence in Religious Certification: A Comprehensive Review of Halal Digitalization, Compliance Integrity, and Future Directions. [PDF]
Riaz MN, Irshad F, Haider MB.
europepmc +1 more source
Niche Overlap Is Not Enough: Same Overlap, Contrasting Fluctuations. [PDF]
Goldberg A +3 more
europepmc +1 more source

