Results 41 to 50 of about 589,833 (361)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Promoting Consumer Adoption of Electric Vehicles from a Standard-Information-Behavior Perspective

open access: yesInformation, 2022
Consumer adoption of electric vehicles is essentially related to product quality factors, such as safety, performance and compatibility; however, the relationship between product quality standards and consumer behavior is not clear.
Weiwei Sun, Min Yuan, Zheng Zhang
doaj   +1 more source

Children and chemical substances in their diet [PDF]

open access: yes
In 2006 a national food consumption survey was conducted commissioned by the Minister of Health, Welfare and Sport. This food consumption survey was focused on the intake of food by young children.
Netherlands Food and Consumer Product Safety Authority
core   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Trouble in Toyland: The 24th Annual Survey of Toy Safety [PDF]

open access: yes, 2009
Details findings on toys that may pose choking hazards, are excessively loud, or contain lead and phthalates. Offers recommendations for consumers, policy makers, and the Consumer Product Safety Commission.

core  

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Identifying leading indicators of product recalls from online reviews using positive unlabeled learning and domain adaptation

open access: yes, 2017
Consumer protection agencies are charged with safeguarding the public from hazardous products, but the thousands of products under their jurisdiction make it challenging to identify and respond to consumer complaints quickly.
Bhat, Shreesh Kumara, Culotta, Aron
core   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

open access: yesFEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc   +8 more
wiley   +1 more source

What must be done to prevent another humidifier disinfectant disaster? [PDF]

open access: yesEnvironmental Health and Toxicology, 2016
The humidifier disinfectant disaster (HDD) was not a simple poisoning accident by biocides, but a singular disaster in history created by chemicals in household products.
Jong-Hyeon Lee
doaj   +1 more source

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