Results 31 to 40 of about 944,347 (309)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

THE PRESENT EPIDEMIOLOGICAL CHARACTERISTICS OF YERSINIOSIS IN THE RUSSIAN FEDERATION

Инфекция и иммунитет, 2018
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E. A. Voskresenskaya, G. I. Kokorina, E. B. Ezhlova, Yu. V. Demina, N. D. Pakskina, O. N. Skudareva   +5 more
doaj   +1 more source

Assessing immunogenicity and protectiveness of the vaccinia virus LIVP-GFP in three laboratory animal models

Инфекция и иммунитет, 2022
Smallpox eradication and lack of adequate animal model for smallpox infection underlies a necessity to assess immunogenic and protective properties of genetic engineering-created live attenuated smallpox vaccines in several animal models of orthopoxviral
S. N. Shchelkunov, A. A. Sergeev, S. N. Yakubitskyi, K. A. Titova, S. A. Pyankov   +4 more
doaj   +1 more source

Fair Is Fair—Reshaping Alaska’s Unfair Trade Practices and Consumer Protection Act [PDF]

, 2011
Few fields of law impact as wide a swath of population as consumer protection law. Alaska adopted its consumer protection statute, the Unfair Trade Practices and Consumer Protection Act (UTPCPA), amid a national movement to strengthen consumer protection
O\u27Quinn, Ryan P., Watterson, Thomas
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Questions of Immunization in Preparation for the XXII Olympic Winter Games and XI Paralympic Winter Games of 2014 in Sochi

Эпидемиология и вакцинопрофилактика, 2015
The data for the immunization of the population of Sochi resort and the staff during preparation for the XXII Olympic Winter Games and XI Paralympic Winter Games of 2014 in Sochi are presented.
G. G. Onishhenko, A. Ju. Popova, I. V. Bragina, E. B. Ezhlova, Ju. V. Demina, A. A. Mel’Nikova, N. V. Frolova, N. D. Pakskina, V. P. Klinduhov, T. V. Grechanaja, P. N. Nikolaevich, M. I. Balaeva, S. Ch. Tesheva, V. V. Parhomenko, A. N. Kulichenko, D. G. Ponomarenko, G. M. Grizhebovsky, T. V. Taran, D. V. Efremenko, A. D. Antonenko   +19 more
doaj   +1 more source

Factors affecting the public judgement of consumer protection authorities [PDF]

, 2012
The article first introduces the state-provided institutions for consumer protection in Hungary, then examines and systematises those factors having a significant impact on the public judgement of the work of consumer protection authorities. The study is
Csiszár, Csilla Margit
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Genetic diversity of the mumps viruses (Paramyxoviridae: Orthorubulavirus: Mumps orthorubulavirus): an overview

Вопросы вирусологии, 2022
Mumps is an infectious disease controlled by specific vaccine prophylaxis. To date, its social and epidemiological significance remains high. This is evidenced by the process of developing and implementing into the health care practices of many countries
T. S. Chekhlyaeva, D. V. Erokhov, I. Yu. Andrievskaya, P. E. Zherdeva, N. T. Tikhonova   +4 more
doaj   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source