Results 41 to 50 of about 82,790 (261)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Questions of Immunization in Preparation for the XXII Olympic Winter Games and XI Paralympic Winter Games of 2014 in Sochi

Эпидемиология и вакцинопрофилактика, 2015
The data for the immunization of the population of Sochi resort and the staff during preparation for the XXII Olympic Winter Games and XI Paralympic Winter Games of 2014 in Sochi are presented.
G. G. Onishhenko, A. Ju. Popova, I. V. Bragina, E. B. Ezhlova, Ju. V. Demina, A. A. Mel’Nikova, N. V. Frolova, N. D. Pakskina, V. P. Klinduhov, T. V. Grechanaja, P. N. Nikolaevich, M. I. Balaeva, S. Ch. Tesheva, V. V. Parhomenko, A. N. Kulichenko, D. G. Ponomarenko, G. M. Grizhebovsky, T. V. Taran, D. V. Efremenko, A. D. Antonenko   +19 more
doaj   +1 more source

Assessing immunogenicity and protectiveness of the vaccinia virus LIVP-GFP in three laboratory animal models

Инфекция и иммунитет, 2022
Smallpox eradication and lack of adequate animal model for smallpox infection underlies a necessity to assess immunogenic and protective properties of genetic engineering-created live attenuated smallpox vaccines in several animal models of orthopoxviral
S. N. Shchelkunov, A. A. Sergeev, S. N. Yakubitskyi, K. A. Titova, S. A. Pyankov   +4 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Genetic diversity of the mumps viruses (Paramyxoviridae: Orthorubulavirus: Mumps orthorubulavirus): an overview

Вопросы вирусологии, 2022
Mumps is an infectious disease controlled by specific vaccine prophylaxis. To date, its social and epidemiological significance remains high. This is evidenced by the process of developing and implementing into the health care practices of many countries
T. S. Chekhlyaeva, D. V. Erokhov, I. Yu. Andrievskaya, P. E. Zherdeva, N. T. Tikhonova   +4 more
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Anthelmintic resistance against benzimidazoles and macrocyclic lactones in strongyle populations on cattle farms in northern Germany

Scientific Reports
Anthelmintic resistance (AR) in cattle gastrointestinal nematodes (GIN) is an increasing global concern, with low to moderate levels recently documented in Central Europe.
Paula Ehnert, Jürgen Krücken, Stefan Fiedler, Fabian Horn, Christina S. Helm, Ann Neubert, Wiebke Weiher, Werner Terhalle, Stephan Steuber, Ricarda Daher, Georg von Samson-Himmelstjerna   +10 more
doaj   +1 more source

RADIATION CONDITIONS IN KALUGA REGION 30 YEARS AFTER CHERNOBYL NPP ACCIDENT

Радиационная гигиена, 2016
The article describes radiation conditions in the Kaluga region 30 years after the Chernobyl NPP accident. The Chernobyl NPP accident caused radioactive contamination of nine Kaluga region territories: Duminichsky, Zhizdrinsky, Kuibyshevsky, Kirovsky ...
A. G. Ashitko, D. V. Zolochevskiy, O. V. Ovsyannikova, S. A. Rozhkova   +3 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source