Results 61 to 70 of about 4,035,157 (323)

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Consumer Protection in an Online World: An Analysis of Occupational Licensing

American Economic Journal: Applied Economics, 2020
We study the demand and supply implications of occupational licensing using transaction-level data from a large online platform for home improvement services.
Chiara Farronato, Andrey Fradkin, B. Larsen, Erik Brynjolfsson   +3 more
semanticscholar   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Consumer law in Constitution: a big mistake? The specific case of aviation in Brazil [PDF]

, 2017
Globalisation, alongside with the growth in trade and wealth has influenced the considerable development of consumer law over the last 50 years. In some countries, consumer rights have been embraced at the highest Constitutional level.
Defossez, Delphine
core   +2 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Anthelmintic resistance against benzimidazoles and macrocyclic lactones in strongyle populations on cattle farms in northern Germany

Scientific Reports
Anthelmintic resistance (AR) in cattle gastrointestinal nematodes (GIN) is an increasing global concern, with low to moderate levels recently documented in Central Europe.
Paula Ehnert, Jürgen Krücken, Stefan Fiedler, Fabian Horn, Christina S. Helm, Ann Neubert, Wiebke Weiher, Werner Terhalle, Stephan Steuber, Ricarda Daher, Georg von Samson-Himmelstjerna   +10 more
doaj   +1 more source

RADIATION CONDITIONS IN KALUGA REGION 30 YEARS AFTER CHERNOBYL NPP ACCIDENT

Радиационная гигиена, 2016
The article describes radiation conditions in the Kaluga region 30 years after the Chernobyl NPP accident. The Chernobyl NPP accident caused radioactive contamination of nine Kaluga region territories: Duminichsky, Zhizdrinsky, Kuibyshevsky, Kirovsky ...
A. G. Ashitko, D. V. Zolochevskiy, O. V. Ovsyannikova, S. A. Rozhkova   +3 more
doaj   +1 more source

Study on Antiviral Activity and Pharmacological Safety of Double-Stranded Ribonucleic Acid for Intranasal Administration

Антибиотики и Химиотерапия, 2022
Interferon inducers are of interest as the first line of defense against viral infections, including influenza. Double-stranded ribonucleic acid (dsRNA) for intranasal administration has been developed, the excipients and drug components were selected at
S. G. Gamaley, G. G. Shimina, E. S. Tsyplenkova, O. V. Simakova, M. O. Skarnovich, M. A. Skarnovich, L. N. Shishkina, O. S. Taranov, O. S. Ivanova, G. M. Levagina, E. D. Danilenko   +10 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Radiation conditions in the Oryol region territory impacted by radioactive contamination caused by the Chernobyl NPP accident

Радиационная гигиена, 2016
Research objective is retrospective analysis of radiation conditions in the Oryol region during 1986- 2015 and assessment of efficacy of the carried out sanitary and preventive activities for population protection against radiation contamination caused ...
G. L. Zakharchenko, E. N. Pereverzeva, A. A. Vasilev, E. V. Polyakova, S. N. Milovanov   +4 more
doaj   +1 more source