Results 61 to 70 of about 104,335 (316)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Review of the existing maximum residue levels for fluopyram according to Article 12 of Regulation (EC) No 396/2005

EFSA Journal, 2020
According to Article 12 of Regulation (EC) No 396/2005, EFSA has reviewed the maximum residue levels (MRLs) currently established at European level for the pesticide active substance fluopyram.
European Food Safety Authority (EFSA), Maria Anastassiadou, Giovanni Bernasconi, Alba Brancato, Luis Carrasco Cabrera, Luna Greco, Samira Jarrah, Aija Kazocina, Renata Leuschner, Jose Oriol Magrans, Ileana Miron, Stefanie Nave, Ragnor Pedersen, Hermine Reich, Alejandro Rojas, Angela Sacchi, Miguel Santos, Alois Stanek, Anne Theobald, Benedicte Vagenende, Alessia Verani   +20 more
doaj   +1 more source

Effect of Direct-to-Consumer Genomewide Profiling to Assess Disease Risk [PDF]

New England Journal of Medicine, 2011
The use of direct-to-consumer genomewide profiling to assess disease risk is controversial, and little is known about the effect of this technology on consumers. We examined the psychological, behavioral, and clinical effects of risk scanning with the Navigenics Health Compass, a commercially available test of uncertain clinical validity and utility.We
Cinnamon S, Bloss, Nicholas J, Schork, Eric J, Topol   +2 more
openaire   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

A comparison of risk assessments on Campylobacter in broiler meat

, 2009
In recent years. several quantitative risk assessments for Campylobacter in broiler meat have been developed to support risk managers in controlling this pathogen.
van der Logt, Peter, Fetsch, A., Dep IRAS, Nauta, Maarten, Risk Assessment of Toxic and Immunomodulatory Agents, Havelaar, A.H., Fazil, A., Havelaar, Arie, Katsma, E., Fetsch, Alexandra, Borck, Birgitte, Borck, B., Rosenquist, Hanne, Katsma, Elly, Christensen, B., Nauta, M., Hill, Andy, Brynestad, S., Katsma, W.E.A., Brynestad, Sigrid, Rosenquist, H., Hill, A., Fazil, Aamir, Christensen, Bjarke Bak, Logt, P., van der, Havelaar, A., van der Logt, P.   +26 more
core   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Fullerene nanosheets for surface-enhanced Raman spectroscopy

ChemPhysMater
Most surface-enhanced Raman scattering (SERS) substrates are based on noble metals or transition metal semiconductors. Developing nonmetallic SERS substrates is of great significance for expanding the application scope of SERS substrate materials.
Linchangqing Yang, Yahui Li, Wei Liu, Junhao Zhang, Qinghong Kong, Guangcheng Xi   +5 more
doaj   +1 more source

Consumer finance: challenges for operational research

, 2010
Consumer finance has become one of the most important areas of banking, both because of the amount of money being lent and the impact of such credit on global economy and the realisation that the credit crunch of 2008 was partly due to incorrect ...
Thomas, Lyn C.
core   +1 more source

Using Human Biomonitoring Data to Support Risk Assessment of Cosmetic Ingredients—A Case Study of Benzophenone-3 [PDF]

, 2022
Safety assessment of UV filters for human health by the Scientific Committee on Consumer Safety (SCCS) is based on the estimation of internal dose following external (skin) application of cosmetic products, and comparison with a toxicological reference ...
Wildeman, Jenna, Qasim Chaudhry, Jenna Wildeman, Marjolijn Woutersen, Bil, Wieneke, Rousselle, Christophe, Wieneke Bil, Meslin, Matthieu, Tamar Berman, Chaudhry, Qasim, Christophe Rousselle, Woutersen, Marjolijn, Berman, Tamar, Matthieu Meslin   +13 more
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source