Results 71 to 80 of about 773,445 (309)

Consumer preferences for teledermoscopy screening to detect melanoma early [PDF]

, 2016
Introduction: ‘Store and forward’ teledermoscopy is a technology with potential advantages for melanoma screening. Any large-scale implementation of this technology is dependent on consumer acceptance.
Janda, Monika, Soyer, H. Peter, Spinks, Jean, Whitty, Jennifer A   +3 more
core   +2 more sources

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

An inter-laboratory study characterizes the impact of bioinformatic approaches on genome-based cluster detection for foodborne bacterial pathogens

Frontiers in Microbiology
Accurate assignment of whole-genome sequences to clusters in foodborne outbreak investigations remains challenging. Variability in bioinformatics tools and quality metrics significantly impacts clustering outcomes.
Leonie F. Forth, Burkhard Malorny, Markus Bönn, Erik Brinks, Grégoire Denay, Carlus Deneke, Hosny El-Adawy, Jennie Fischer, Jannika Fuchs, Ekkehard Hiller, Nancy Bretschneider, Sylvia Kleta, Stefanie Lüth, Tilman Schultze, Henning Petersen, Michaela Projahn, Christian Schäfers, Kerstin Stingl, Andreas J. Stroehlein, Laura Uelze, Kathrin Szabo, Anne Wöhlke, Jörg Linde   +22 more
doaj   +1 more source

Reasoned opinion on the review of the existing maximum residue levels (MRLs) for prothioconazole according to Article 12 of Regulation (EC) No 396/2005 [PDF]

EFSA Journal, 2014
According to Article 12 of Regulation (EC) No 396/2005, the European Food Safety Authority (EFSA) has reviewed the Maximum Residue Levels (MRLs) currently established at European level for the pesticide active substance prothioconazole.
European Food Safety Authority
doaj   +1 more source

On increasing of the competitiveness of the garment industry in Siberian Federal District on the basis of the industrial cluster establishment [PDF]

, 2016
The issue of the development prospects of the Russian economy and the economy of its individual branches in the regions is highly relevant in terms of the increasing crises and economic development challenges. The scope of the study is a garment industry
Rodina, L. A., Sinyavets, T. D.
core   +1 more source

Principle considerations for the risk assessment of sprayed consumer products

Toxicology Letters, 2014
In recent years, the official regulation of chemicals and chemical products has been intensified. Explicitly for spray products enhanced requirements to assess the consumers'/professionals' exposure to such product type have been introduced. In this regard the Aerosol-Dispensers-Directive (75/324/EEC) with obligation for marketing aerosol dispensers ...
Steiling, W., Bascompta, M., Carthew, P., Catalano, G., Corea, N., D’Haese, A., Jackson, P., Kromidas, L., Meurice, P., Rothe, H., Singal, M.   +10 more
openaire   +2 more sources

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Reasoned opinion on the review of the existing maximum residue levels (MRLs) for dodine according to Article 12 of Regulation (EC) No 396/2005 [PDF]

EFSA Journal, 2015
According to Article 12 of Regulation (EC) No 396/2005, the European Food Safety Authority (EFSA) has reviewed the Maximum Residue Levels (MRLs) currently established at European level for the pesticide active substance dodine.
European Food Safety Authority
doaj   +1 more source

Safety assessment of the process ‘Plastienvase’, based on EREMA Basic technology, used to recycle post-consumer PET into food contact materials [PDF]

, 2017
Publisher ...
Bolognesi, Claudia, Castle, Laurence, Cravedi, Jean-Pierre, Dudler, Vincent, EFSA Panel on Food Contact Materials Enzymes, Flavourings and Processing Aids (CEF), Engel, Karl-Heinz, Fowler, Paul, Gontard, Nathalie, Grob, Konrad, Gürtler, Rainer, Husøy, Trine, Kärenlampi, Sirpa, Lampi, Eugenia, Mennes, Wim, Milana, Maria Rosaria, Nerin, Cristina, Papaspyrides, Constantine, Penninks, André, Silano, Vittorio, Smith, Andrew, Tavares Poças, Maria de Fátima, Tlustos, Christina, Volk, Katharina, Wölfle, Detlef, Zorn, Holger, Zugravu, Corina-Aurelia   +25 more
core   +3 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source