Results 41 to 50 of about 786,315 (288)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

EPIDEMIOLOGICAL RISK OF INTRODUCTION OF DANGEROUS AND EXOTIC INFECTIOUS DISEASES ON THE TERRITORY OF THE XXII OLYMPIC WINTER GAMES AND XI PARALYMPIC WINTER GAMES 2014 IN SOCHI

Журнал микробиологии, эпидемиологии и иммунобиологии, 2015
To assess the epidemiological risk of introduction of serious infectious diseases in the pre-Olympic period defined list of dangerous and exotic infections and held assessment ofpotential danger threatening.
B. P Kuzkin, E. B Ezhlova, A. N Kulichenko, O. V Maletskaya, Yu. V Demina, T. V Taran, N. D Pakskina, T. V Kharchenko, G. M Grizhebovsky, V. N Savelev, V. G Oroby, V. P Klindukhov, T. V Grechanaya, S. Ch Tesheva, G. D Bryukhanova   +14 more
doaj  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Epidemiological Features of New Coronavirus Infection (COVID-19). Communication 1: Modes of Implementation of Preventive and Anti-Epidemic Measures

Проблемы особо опасных инфекций, 2020
The review analyses the information on the epidemiological situation on COVID-19 around the world. Presented is the assessment of the major epidemiological parameters (basic reproductive rate, lethality, incubation period, and serial interval ...
V. V. Kutyrev, A. Yu. Popova, V. Yu. Smolensky, E. B. Ezhlova, Yu. V. Demina, V. A. Safronov, I. G. Karnaukhov, A V. Ivanova, S. A. Shcherbakova   +8 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Scientific and methodical development of biotechnological production of immunobiological preparations for instant diagnosis of infectious diseases and detection of pathogens

Биопрепараты: Профилактика, диагностика, лечение, 2018
The present article describes the scientific and methodological development of biotechnological manufacture of test-system components (diagnostic preparations) for instant diagnosis of plague, brucellosis, tularemia, anthrax, cholera.
I. S. Tyumentseva, I. V. Zharnikova, E. N. Afanasiev, V. I. Efremenko, O. I. Kogotkova, S. M. Kalnoy, A. N. Kulichenko   +6 more
doaj  

Species identification of diphyllobothriosis causative agent Dibothriocephalus nihonkaiensis found in the summer chum O. keta during spawning migration in the Amur River

Российский паразитологический журнал
The purpose of the research is the species identification of Dibothriocephalus spp. plerocercoids in the summer chum Oncorhynchus keta caught in the Amur River based on analysis of a cytochrome c-oxidase subunit 1 (COX1) gene fragment of mitochondrial ...
A. G. Dragomeretskaya, Yu. I. Moskvina, V. O. Kotova, E. V. Podorozhnyuk, O. E. Trotsenko, S. I. Gaer   +5 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Phylogeny and Classification of Yersinia pestis Through the Lens of Strains From the Plague Foci of Commonwealth of Independent States

Frontiers in Microbiology, 2018
The established phylogeny of the etiological agent of plague, Yersinia pestis, is not perfect, as it does not take into account the strains from numerous natural foci of Commonwealth of Independent States (CIS).
Vladimir V. Kutyrev, Galina A. Eroshenko, Vladimir L. Motin, Vladimir L. Motin, Nikita Y. Nosov, Jaroslav M. Krasnov, Lyubov M. Kukleva, Konstantin A. Nikiforov, Zhanna V. Al’khova, Eugene G. Oglodin, Natalia P. Guseva   +10 more
doaj   +1 more source