Results 81 to 90 of about 1,341,424 (311)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Status Quo and Future Challenges for the Research Infrastructure in the Field of Culture [PDF]

open access: yes
The term "culture" is notorious for the multitude of its meanings. This expertise strictly focuses on culture in terms of the arts. We adopt a sociological as well as an economic perspective. Research questions are subdivided into three spheres of action:
Gunnar Otte, Jörg Rössel
core  

Culture of Consumption

open access: yes, 2003
An encyclopedia piece 
openaire   +2 more sources

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

What Did Slaves Wear? Textile Regimes In The French Caribbean [PDF]

open access: yes, 2012
This study of the dress of enslaved men and women in the French Antilles is based on a critical examination of written and pictorial sources. Analyzing work clothes, by law masters’ responsibility, and festive apparel, which slaves themselves procured ...
DuPlessis, Robert S.
core   +3 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Cookbook choice a matter of self-identity [PDF]

open access: yes, 2008
Cookbooks have long been recognised as more than instructional texts rather as a literary genre with narratives beyond the functional. This paper discusses the influences which guide choices of cookbook and cookery writer for a group of thirtysomethings ...
Tonner, A.
core  

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