Results 71 to 80 of about 305,802 (266)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Tüketim Kültüründe Kadın Bedeninin İdealize Edilmesine Yönelik Kadın Algılamaları ve Tüketim Davranışlarıyla İlişkisi

open access: yesSelçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2010
Bu çalışmanın amacı, tüketim kültüründe kadın bedeninin idealize edilmesine yönelik kadın algılamalarınıtespit etmek ve bu algılamaların tüketim ile ilgili kendi davranışve tutumlarına nasıl yansıdığınıortaya koymaktır.
Serap Yücel Doğan
doaj  

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

DESIGN AS A STANDPOINT IN MODERN CONSUMPTION CULTURE

open access: yesDaya, 2018
Design acts as a bridge between the production and consumption of goods, graphic communications, appa-rel, spaces, etc. Design has materialized life expectancies which were built within Modernity and Postmoder-nity.
Xavier Jiménez Álvaro
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Tüketim Hedonizminden Gözetime Açık Bilet: HOPİ Akıllı Kart Uygulaması Örneği

open access: yesYeni Medya, 2018
Modern birey kapitalist tüketim kültürünün kendisine yaşattığı tüketim hazzını yaşamak ve kendisini “o” ürünü tüketerek bir statünün içine dahil etmek hayalindedir.
Gözde Şahin
doaj  

Between Two Worlds: an Ethnographic Study of Gay Consumer Culture in Rio de Janeiro [PDF]

open access: yesBAR: Brazilian Administration Review, 2012
It is not easy to study socially marginalized groups such as gays, ethnic minorities, and others. This is, however,an extremely relevant topic in the consumer behavior area since the status of members of a modern consumersociety is largely denied to ...
Severino Joaquim Nunes Pereira   +1 more
doaj  

Cultural Differences and the Consumption Structure in the European Union Countries

open access: yesActa Universitatis Lodziensis. Folia Oeconomica, 2019
The aim of the paper is to study the cultural differentiation in the European Union countries and compare it with the differentiation in their consumption spending.
Mateusz Jankiewicz
doaj   +1 more source

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