Heterotropic regulation and negative homotropic cooperativity
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Dynamics of Military Procurement: Changes in Military Consumption Patterns [PDF]
human development, consumption ...
Arjan de Haan, Michael Lipton
core
Eating for performance: an evaluation of food consumption patterns and adherence to dietary guidelines in elite wheelchair basketball players. [PDF]
Norte A +11 more
europepmc +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Environmentally sustainable houshold consumption: From aggregate environmental pressures to indicators for priority fields of action [PDF]
During the UNCED conference in Rio de Janeiro 1992 unsustainable consumption and production patterns were identified as one of the key driving forces behind theunsustainable development of the world (Agenda 21, chapter 4).
Lorek, Sylvia, Spangenberg, Joachim H.
core
Recognition of Food Processing and Its Association with Consumption Patterns and Nutrient Intake Among Saudi University Students. [PDF]
Alomari WD, Almoraie NM.
europepmc +1 more source
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source
Stock Ownership Patterns, Stock Market Fluctuations, and Consumption [PDF]
macroeconomics, Stock Ownership Patterns, Stock Market Fluctuations ...
James M. Poterba, Andrew A. Samwick
core
Impact of milk consumption patterns on cow's milk sensitization and allergy in at-risk children. [PDF]
Azani L +3 more
europepmc +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source

