Results 131 to 140 of about 3,549,018 (318)

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Profile and Visual Outcome of Patients having Keratoconus Attending Tertiary Eye Hospital, Nepal

Journal of Nobel Medical College
Background: Keratoconus is a bilateral, asymmetric, chronic, progressive ectasia of the cornea in which patients experience distorted vision that is usually treated with rigid contact lenses when spectacles no longer provide adequate vision.
Pankaj Ray Adhikari, Nirmala Chaudhary, Rajiv Ranjan Karn   +2 more
doaj   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source

Contact Lens History, Contact Lens Types and Future of Contact Lens

Kırklareli Üniversitesi Mühendislik ve Fen Bilimleri Dergisi
With the rapid development of technology, the use of different materials and device production for sharp vision has accelerated. One of the areas that benefit from developing technology is contact lens technology. In this study, the production-development stages of contact lenses, contact lens types, and materials used in production were investigated ...
Hülya Kuru Mutlu, Malik Kaya, Armağan Kırankabeş   +2 more
openaire   +2 more sources

RETRACTION: Mechanism of p27 Upregulation Induced by Downregulation of Cathepsin B and Upar in Glioma

Molecular Oncology, EarlyView.
RETRACTION: S. Gopinath, K. Alapati, R. R. Malla, C. S. Gondi, S. Mohanam, D. H. Dinh, and J. S. Rao, “Mechanism of p27 Upregulation Induced by Downregulation of Cathepsin B and Upar in Glioma,” Molecular Oncology 5, no. 5 (2011): 426–437, https://doi.org/10.1016/j.molonc.2011.07.004.
wiley   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Benchmarking Signorini and exponential contact laws for an industrial train brake squeal application [PDF]

, 2012
Contact representation of structure interactions for finite element models is nowadays of great interest in the industry. Two contact modellig strategies exist in the literature, either based on a perfect contact with no interpenetration of structures at
VERMOT DES ROCHES, Guillaume, BALMES, Etienne, LORANG, Xavier, CHIELLO, Olivier   +3 more
core  

Secondary transfer effects of intergroup contact : Alternative accounts and underlying processes

, 2010
Although intergroup contact is one of the most prominent interventions to reduce prejudice, the generalization of contact effects is still a contentious issue.
Nicole Tausch, Psaltis, C., Schmid, K, Katharina Schmid, Schmid, K., Cairns, E., Kenworthy, Jared B., Hughes, Joanne, Cairns, E, Tausch, Nicole, Joanne Hughes, Tausch, N, Kenworthy, JB, Psaltis, Charis, Hughes, J, Miles Hewstone, Hewstone, Miles, Jared B. Kenworthy, Ed Cairns, Hewstone, M., Popan, J.R., Psaltis, C, Hewstone, M, Kenworthy, J.B., Jason R. Popan, Cairns, Ed, Charis Psaltis, Popan, Jason R., Popan, JR, Schmid, Katharina, Tausch, N.   +30 more
core   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Humanoid facial expressions as a tool to study human behaviour

Scientific Reports
Besides action vitality forms, facial expressions represent another fundamental social cue which enables to infer the affective state of others. In the present study, we proposed the iCub robot as an interactive and controllable agent to investigate ...
G. Lombardi, A. Sciutti, F. Rea, F. Vannucci, G. Di Cesare   +4 more
doaj   +1 more source