Disentangling genetic and environmental risk factors for individual diseases from multiplex comorbidity networks [PDF]
Most disorders are caused by a combination of multiple genetic and/or environmental factors. If two diseases are caused by the same molecular mechanism, they tend to co-occur in patients. Here we provide a quantitative method to disentangle how much genetic or environmental risk factors contribute to the pathogenesis of 358 individual diseases ...
arxiv
Dupilumab for bullous pemphigoid with intractable pruritus [PDF]
Bullous pemphigoid (BP) is an autoimmune blistering disorder that predominantly affects the elderly. Treatment regimens typically include topical and systemic immunosuppressive medications.
Eichenfield, Dawn Z+2 more
core
ABSTRACT Alkyl polyglucosides (APG) are biodegradable, non‐ionic surfactants from renewable sources with low ecotoxicity. This study developed a novel PEG‐free nanoemulsion (NE) using APG to encapsulate Baccharis dracunculifolia essential oil (BDO) for skin repair.
Carolina Sousa Ponciano+7 more
wiley +1 more source
Evaluation of contact sensitivity to topical drugs in patients with contact dermatitis [PDF]
Background and Design: Topical drugs are an important group of contact allergens. The present study aimed to evaluate contact sensitivity to topical drugs in patients with contact dermatitis.
Aynur Akyol+2 more
core
Allergic contact dermatitis to Aloe vera [PDF]
We present the case of a 72-year-old woman observed for dermatitis on the legs followed by apperance of erythema on the eyelids. She had a past history of peripheral venous insufficiency and had been using self home-made Aloe vera juice over the legs for
Ferreira, M.+3 more
core +1 more source
Role of Topical Ketoconazole in Therapeutic Hair Care Beyond Seborrhoeic Dermatitis and Dandruff
ABSTRACT Ketoconazole shampoo has well‐documented consistent efficacy and safety in treating dandruff and seborrhoeic dermatitis (SD) when compared to other active antidandruff ingredients such as selenium sulphide, corticosteroids and zinc pyrithione.
Aditya K. Gupta+2 more
wiley +1 more source
Protective effect of small molecule analogues of the Acanthocheilonema viteae secreted product ES-62 on oxazolone-induced ear inflammation [PDF]
ES-62 is the major secreted protein of the rodent filarial nematode Acanthocheilonema viteae. The molecule contains covalently attached phosphorylcholine (PC) residues, which confer anti-inflammatory properties on ES-62, underpinning the idea that drugs ...
Ahlfors+31 more
core +1 more source
Methyldibromoglutaronitrile (MDBGN) is a preservative found in cosmetics as well as in products for industrial use. It caused an outbreak of allergic contact dermatitis in Europe in the 1990s and early 2000s.
Maher Maoua
doaj +1 more source
Differential diagnosis of contact dermatitis: A practical-approach review by the EADV Task Force on contact dermatitis. [PDF]
The diagnosis of eczema ('dermatitis') is mostly clinical and depends on the clinical history and exploratory objective findings (primary lesions, patterns).
Aerts, Olivier+15 more
core +1 more source
Genital Psoriasis: Shining Light on This Hidden Disease
Psoriasis occurring on skin of the genital and perigenital regions has specific diagnostic and treatment requirements due to the sensitivity and private nature of these areas. A multidisciplinary group of experts in the management of genital psoriasis, the Genital Psoriasis Wellness Consortium, convened to discuss the impact of genital psoriasis on ...
Jennifer Cather+19 more
wiley +1 more source