Results 41 to 50 of about 3,517,154 (297)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Strain-rate-dependent model for the elastoplastic dynamic contact of sphere and plate

open access: yesMaterials Research Express, 2020
A force-indentation contact model is presented for the dynamic contact loading of elastoplastic particle and plate to incorporate the material’s strain-rate-dependent plasticity, built theoretically from the well-known Hertz contact law and Hill’s ...
Tengfei Jin   +5 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Application of optical measurement techniques to high strain rate deformations in composite materials [PDF]

open access: yes, 2010
Traditionally high strain rate material characterisations have been conducted using strain gauges and/or cross head displacements in servo-hydraulic test machines, and force transducers in split Hopkinson bar experiments.
Syngellakis, Stavros   +8 more
core   +1 more source

Contact Load Measurement and Validation for Tapered Rollers in Wind Turbine Main Bearing

open access: yesSensors
Addressing the need for contact load detection in wind turbine main bearings during service, a roller contact load measurement method is proposed. An analytical model characterizes the contact load-to-inner bore strain mapping relationship.
Zhenggang Guo   +3 more
doaj   +1 more source

Influence of Microscopic Parameters on the Stress-Strain Relation in Rocks

open access: yesAdvances in Civil Engineering, 2018
Macromaterial properties should correspond to the mesoscopic parameters simulated in practical engineering problems. Discrete element contains a variety of particle models and its corresponding mesoscopic parameters, and the one-to-one relationship ...
Yanhui Cheng, Weijun Yang
doaj   +1 more source

Estimation of contact characteristics based on measurement of inner tire surface strain

open access: yesNihon Kikai Gakkai ronbunshu, 2014
From a point of view of handling and stability, it is important to bring automotive tires into contact with the road correctly. If the contact state of the tire is known while moving, more advanced vehicle control can be carried out.
Shigeyuki YAMABE   +5 more
doaj   +1 more source

Numerical simulation of elastoplastic contact of heavy-loaded spiroid gears [PDF]

open access: yesMATEC Web of Conferences, 2019
The paper presents the analysis of heavy-loaded low-speed multi-pair spiroid gears under the effect of elastic contact, bending and shearing, and elastoplastic contact interaction of spiroid gearwheel teeth and spiroid worm threads.
Sannikov Alexander
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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