Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Fatigue analysis of catenary contact wires for high speed trains [PDF]
The fatigue fracture is one of the most critical failures which may occur on the high speed network because it is undetectable and it has a huge impact on traffic disruption.
MAITOURNAM, Habibou +4 more
core
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Therapeutic contact lenses were developed from bacterial ...
Cavicchioli, Maurício +17 more
core +1 more source
Xenobiotics in the environment: abiotic transformation and toxicity [PDF]
[ITALIANO] La presenza nell'ambiente di sostanze chimiche (pesticidi, farmaci, etc.) potrebbe rappresentare un rischio per la salute umana. Pertanto, è importante avere informazioni sul destino ambientale di tali xenobiotici che possono persistere nelle ...
Rubino, Maria
core +1 more source
Chemical composition and insecticidal efficacy of essential oil of Echinophora platiloba DC (Apiaceae) from Zagros foothills, Iran [PDF]
Essential oil of Echinophora platyloba was screened for its chemical composition and possible fumigant and contact toxicity effects against Tribolium castaneum (Herbst), Callosobruchus maculatus (F.) and Rhyzopertha dominica (F.).
Iman Sharifian, Ali Darvishzadeh
doaj
Creating high-efficient and environment-friendly pesticides is very important to produce the pollution free agriculture food and maintain the balance of the survival environmental of the human being.
Li DENG +6 more
doaj +1 more source
FUMIGANT AND CONTACT TOXICITY OF GARLIC OIL ON Ca/losobruchus c/Jinensis (L.), CaJJosobruchus macuJatus (F.), Tribolium castaneum (HBST.) AND SitophiJus oryzae (L.) [PDF]
Toxicity of garlic oil was tested against adults of Callosobruchus chinensis (L.), C. maculatus (F.), Tribolium castaneum(Hbst.) and Sitophilus oryzae(L.) using air tight jars for the fumigant toxicity and topical application for the contact toxicity ...
M. Swidan,
doaj +1 more source
Effects of Piper nigrum L. Fruit Essential Oil Toxicity against Stable Fly (Diptera: Muscidae)
The efficacy of Piper nigrum L. fruit essential oil (EO) against Stomoxys calcitrans (stable fly), a blood-feeding fly distributed worldwide, was investigated.
Thekhawet Weluwanarak +4 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Toxicity of pesticides and their mixture to primary producers [PDF]
The earth’s aquatic ecosystems are threatened by the contamination with a multitude of anthropogenic chemical pollutants. Pesticides are one important group of environmental contaminants.
Knauert, Stefanie
core +1 more source

