Results 51 to 60 of about 10,978 (266)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Securing the Shared Kernel: Exploring Kernel Isolation and Emerging Challenges in Modern Cloud Computing

open access: yesIEEE Access
Containerization is a rapidly advancing technology in cloud computing, facilitating the seamless development, deployment, and management of applications across diverse computing environments.
Sehar Zehra   +5 more
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

eBPF-Based Runtime Detection of Semantic DDoS Attacks in Linux Containers

open access: yesIEEE Access
Modern Distributed Denial-of-Service (DDoS)attacks increasingly target the application layer to exhaust CPU resources and disrupt service availability, particularly in containerized environments where isolation and diverse implementations complicate ...
S. Remya   +7 more
doaj   +1 more source

Secure Containers in Android

open access: yesProceedings of the 6th Workshop on Security and Privacy in Smartphones and Mobile Devices, 2016
Bring Your Own Device (BYOD) is a growing trend among enterprises, aiming to improve workers' mobility and productivity via their smartphones. The threats and dangers posed by the smartphones to the enterprise are also ever-growing. Such dangers can be mitigated by running the enterprise software inside a "secure container" on the smartphone.
Uri Kanonov, Avishai Wool
openaire   +3 more sources

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Predicting Affected Docker Images From Emerging Vulnerabilities With a Tripartite Graph

open access: yesIEEE Access
Containerization is widely adopted across modern software systems, but it also increases exposure to a growing number of security vulnerabilities.
Sungjae Park   +4 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Information Encryption in Ghost Imaging With Customized Data Container and XOR Operation

open access: yesIEEE Photonics Journal, 2017
The conventional ghost-imaging-based encryption (GIE) scheme has low-quality decrypted images and unsatisfied security. In this paper, we propose to cope with these issues using customized data container and exclusive-OR (XOR) operation.
Yi Qin, Yingying Zhang
doaj   +1 more source

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