Results 101 to 110 of about 45,682 (299)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Method of Assessing the Impact of Polish Container Terminals in Reducing the External Costs of Transport

open access: yesPromet (Zagreb), 2013
The paper attempts to identify the social costs and benefits of marine container terminal operations regarding feeder vessels services. It presents a method of valuation which takes into account the external costs of additional factors: the nature and ...
Izabela Kotowska
doaj   +1 more source

Generating scenarios for simulation and optimization of container terminal logistics

open access: yes, 2016
This paper introduces an approach for generating scenarios of sea port container terminals. A scenario consists of arrivals of deep sea vessels, feeder ships, trains, and trucks together with lists of containers to be loaded and unloaded.
Hartmann, Sönke
core  

Branch and price approach for the container relocation problem [PDF]

open access: yes, 2013
Container terminals offer transfer facilities to move containers from vessels to trucks, trains and barges and vice versa. Incoming containers are not immediately loaded on an outgoing vehicle, but stored in the yard for up to several days.
Feillet, Dominique, Zehendner, Elisabeth
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Multicriteria Decision Model for Port Evaluation and Ranking: An Analysis of Container Terminals in Latin America and the Caribbean Using PCA-TOPSIS Methodologies

open access: yesApplied Sciences
In recent years, despite a decline in international trade and disruptions in the supply chain caused by COVID-19, the main container terminals in Latin America and the Caribbean (LAC) have increased their container volumes.
Adriana Pabón-Noguera   +5 more
doaj   +1 more source

L-band, 1.2 m parabolic antenna-noise temperature measurement [PDF]

open access: yes, 1975
Extensive antenna-noise temperature measurements at 1.6 GHz (L-band) were made using a 1.2 m (4 ft. diameter) parabolic dish antenna mounted on the flying bridge of a modern 15,690-ton, commercial-container ship.
Hill, J. S., Taylor, R. E.
core   +1 more source

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