Results 101 to 110 of about 45,682 (299)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
The paper attempts to identify the social costs and benefits of marine container terminal operations regarding feeder vessels services. It presents a method of valuation which takes into account the external costs of additional factors: the nature and ...
Izabela Kotowska
doaj +1 more source
Generating scenarios for simulation and optimization of container terminal logistics
This paper introduces an approach for generating scenarios of sea port container terminals. A scenario consists of arrivals of deep sea vessels, feeder ships, trains, and trucks together with lists of containers to be loaded and unloaded.
Hartmann, Sönke
core
Branch and price approach for the container relocation problem [PDF]
Container terminals offer transfer facilities to move containers from vessels to trucks, trains and barges and vice versa. Incoming containers are not immediately loaded on an outgoing vehicle, but stored in the yard for up to several days.
Feillet, Dominique, Zehendner, Elisabeth
core
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
In recent years, despite a decline in international trade and disruptions in the supply chain caused by COVID-19, the main container terminals in Latin America and the Caribbean (LAC) have increased their container volumes.
Adriana Pabón-Noguera +5 more
doaj +1 more source
L-band, 1.2 m parabolic antenna-noise temperature measurement [PDF]
Extensive antenna-noise temperature measurements at 1.6 GHz (L-band) were made using a 1.2 m (4 ft. diameter) parabolic dish antenna mounted on the flying bridge of a modern 15,690-ton, commercial-container ship.
Hill, J. S., Taylor, R. E.
core +1 more source

