Results 101 to 110 of about 45,740 (299)
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Branch and price approach for the container relocation problem [PDF]
Container terminals offer transfer facilities to move containers from vessels to trucks, trains and barges and vice versa. Incoming containers are not immediately loaded on an outgoing vehicle, but stored in the yard for up to several days.
Feillet, Dominique, Zehendner, Elisabeth
core
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
The paper attempts to identify the social costs and benefits of marine container terminal operations regarding feeder vessels services. It presents a method of valuation which takes into account the external costs of additional factors: the nature and ...
Izabela Kotowska
doaj +1 more source
Generating scenarios for simulation and optimization of container terminal logistics
This paper introduces an approach for generating scenarios of sea port container terminals. A scenario consists of arrivals of deep sea vessels, feeder ships, trains, and trucks together with lists of containers to be loaded and unloaded.
Hartmann, Sönke
core
Global Trade Impacts: Addressing the Health, Social and Environmental Consequences of Moving International Freight Through Our Communities [PDF]
Examines freight transportation industry trends; the impact of global trade on workers, the environment, and health in both exporting and importing countries; and organizing strategies and policy innovations for minimizing the damage and ensuring ...
Andrea Hricko +3 more
core
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source

