Results 61 to 70 of about 3,134 (252)
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Salmonella‐Containing Vacuoles: Directing Traffic and Nesting to Grow [PDF]
Traffic, 2008 Salmonella enterica serovar Typhimurium (S. typhimurium) is a gram‐negative facultative intracellular pathogen that can infect a broad range of mammalian hosts. Following invasion of host cells, the majority of S. typhimurium are known to reside in a membrane‐bound compartment known as the Salmonella‐containing vacuole (SCV).
Malina A, Bakowski +2 more
openaire +2 more sources
Possibility of Increasing Container Traffic in the Port of Koper Due to Introducing the Sea Motorway
, 2010 The aim of this paper is to present the possibility of introducing the motorway of the sea to the Port of Koper. Based on the present situation in the Port of Koper and the planned extension of the container terminal determined by the development plans ...
Urša Horvat
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Mixing it Up: Simulation of Mixed Traffic Container Terminals
2020 Winter Simulation Conference (WSC), 2020 The development from a completely manual brownfield terminal towards a highly automated one proceeds in a number of steps. To take the first steps, it is crucial to know how introducing Automated Yard Tractors (AYTs) influences port productivity at Mixed-Traffic Terminals (MTTs).
Berry Gerrits, Martijn Mes, Peter Schuur
openaire +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Transportation and Information Technologies in RussiaBackground. The article provides an overview of the current state of the railway container transportation market, analyzes statistical data on the dynamics of the railway container transportation market by type of transportation and individual transport ...
Maksim A. Marchenko +2 more
doaj +1 more source