Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Development and justification of technical solutions for the design of a long-base flat car for the transportation of high-capacity containers. [PDF]
Rahimov R, Zafarov D, Khurmatov Y.
europepmc +1 more source
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Robustness of hinterland container transportation
Containerisation has dramatically changed international transportation; it has affected the speed and costs of the transportation of goods. The largest share of costs of container transportation is related to inland transportation. The performance of the
Van Vuure, B. (author)
core
Identifying the significant drivers of containerized freight rates: From the perspective of dynamic multiscale dependence. [PDF]
Chen Y, Feng A, Tang C.
europepmc +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Impact of the Ripple Effect on the Resilience of Multimodal Container Port Operations: A System Dynamics Simulation Approach. [PDF]
Zhang J +6 more
europepmc +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Development of DC Inverter Scroll Compressor used for Marine Container Refrigeration Unit
In recent years, energy saving of a container ship is becoming one of the most important issues from the point of environmental protection of the global marine transportation business. To solve this problem, we have developed a new gas injection inverter
Kato, Katsumi +4 more
core
Impact of smart energy on a three-echelon closed-loop supply chain management with reduction of carbon emissions. [PDF]
Bar N, Sangal I, Sarkar B.
europepmc +1 more source

