Results 131 to 140 of about 641,939 (299)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Integrated scheduling of gantry cranes, container trucks and yard cranes in on‐dock railway operation areas at multimodal container ports

open access: yesIET Intelligent Transport Systems
On‐dock railway operation areas at sea‐rail container ports play a crucial role in transferring containers between maritime and rail transportation systems.
Tian Xia   +5 more
doaj   +1 more source

Containing Containers - Advantages and Risks

open access: yes, 2016
Container, as defined in the dictionary, is an object that can hold something. Extending its meaning: a place where some correlated items can be stored or move together; a separator of things; a constrain for the contained things. Starting in 1982 with chroot, to BSD-jails, Solaris Containers, LXC, OpenVZ, and Docker, container systems try to keep ...
openaire   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Containing China: Containing Temporarily

open access: yes
AbstractPermanent containment of crisis risks is good, permanent containment of states dangerous. Only temporary containment of states works, and only when combined with ongoing dialogue on what states must do to get containment lifted. Temporary re-containment of Russia makes sense at the time of writing because it wages a war of aggression in Ukraine.
openaire   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

La industria del vidrio y el medio ambiente: oportunidad y enfoque del Análisis del Ciclo de Vida

open access: yesBoletín de la Sociedad Española de Cerámica y Vidrio, 2002
The advances in the knowledge of the interaction of human activities with the environment has enabled us to study systematically the available information and to develop assessment systems that permit to have reliable, useful and intercomparable results.
Mari, A.
doaj  

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