Results 131 to 140 of about 641,939 (299)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
On‐dock railway operation areas at sea‐rail container ports play a crucial role in transferring containers between maritime and rail transportation systems.
Tian Xia +5 more
doaj +1 more source
Containing Containers - Advantages and Risks
Container, as defined in the dictionary, is an object that can hold something. Extending its meaning: a place where some correlated items can be stored or move together; a separator of things; a constrain for the contained things. Starting in 1982 with chroot, to BSD-jails, Solaris Containers, LXC, OpenVZ, and Docker, container systems try to keep ...
openaire +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Containing China: Containing Temporarily
AbstractPermanent containment of crisis risks is good, permanent containment of states dangerous. Only temporary containment of states works, and only when combined with ongoing dialogue on what states must do to get containment lifted. Temporary re-containment of Russia makes sense at the time of writing because it wages a war of aggression in Ukraine.
openaire +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
La industria del vidrio y el medio ambiente: oportunidad y enfoque del Análisis del Ciclo de Vida
The advances in the knowledge of the interaction of human activities with the environment has enabled us to study systematically the available information and to develop assessment systems that permit to have reliable, useful and intercomparable results.
Mari, A.
doaj

