Results 141 to 150 of about 234,295 (260)

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Assessing dengue vector breeding in diverse environments for targeted interventions: Case studies from Colombia and Nepal. [PDF]

Curr Res Parasitol Vector Borne Dis
Barahona E, Nelson-Cofie D, Kroeger A, Chavarría K, Vence N, Banjara MR.   +5 more
europepmc   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Interactive Effects of Shading Intensity and Container Type on Growth, Photosynthesis, and the Carbon-Antioxidant Trade-Off in <i>Dalbergia odorifera</i> Seedlings. [PDF]

Plants (Basel)
Zhang M, Chen F, Lin L, Chen L, Yang X, Dong X, Song J, Huang C.   +7 more
europepmc   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Refrigerated Containers

Na početku rada opisuje se pojava brodskih kontejnera te s njima i početak izrade kontejnerskih brodova, a kasnije se rad bazira na rashladnim kontejnerima.
Zovko, Luka
core   +2 more sources

The impact and cost of using mobile digital X-ray units to detect pulmonary TB in South Africa. [PDF]

IJTLD Open
Coetzee L, Evans D, Fononda A, Hausler H, Booyens L, Steingo J, Hirasen K, Jamieson L, Kubjane M, Meyer-Rath G.   +9 more
europepmc   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Enhancing reproducibility in neuroimaging with containerized archival. [PDF]

Brain Imaging Behav
Kim ME, Kanakaraj P, Liu Y, Schwartz T, Li Z, Newlin NR, Gao C, Schilling KG, Bao S, Rogers BP, Landman BA, Ramadass K.   +11 more
europepmc   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source