Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Proactive Initiative to Establish a Dengue-Free Factory Assessment Framework in Dengue High-Risk Industrial Areas: A Narrative Review. [PDF]
Ritthison W +3 more
europepmc +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Endosymbiont-mediated resistance: effects of Hamiltonella defensa (Enterobacterales: Enterobacteriaceae) on parasitism of Aphidius colemani and Praon volucre (Hymenoptera: Braconidae) in Aphis craccivora (Hemiptera: Aphididae). [PDF]
Heidari Latibari M +7 more
europepmc +1 more source
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
[Containers 3_ 01container4.jpg]
3_ 01container4.jpg (file jpeg, 28,222 x 35,278 cm, 72 dpi). Fotografia del primo prototipo del lavoro.3_ 01container4.jpg (file jpeg, 28,222 x 35,278 cm, 72 dpi).
Koike, Kensuke
core
Measuring the impact of virtualization and containerization on the environment when using GPUs for processing the AI models. [PDF]
Hriez S, Haikal M.
europepmc +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Household Characteristics, Residents' Behaviors, and Seasonal Factors Associated With the Presence and Persistence of Aedes aegypti in a Dengue-Endemic Area. [PDF]
Cortés-Meda A +4 more
europepmc +1 more source

