Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Effects of Nixing Pottery Storage on Microbial Community Characteristics, Quality, and Volatile Components of Liupao Tea. [PDF]
Mao J, Wu Y, Chen X, Huang Z.
europepmc +1 more source
Testing Applications Using Linux Containers
This thesis discusses software containers (Docker containers in particular) as a variant of server virtualization. Instead of virtualizing hardware, software containers rest on top of a single operating system instance and are much more efficient than ...
Marhefka, Matúš
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Prioritizing urban water-storage containers for molecular surveillance of invasive <i>Anopheles stephensi</i> in Isiolo, Kenya: An evidence-informed opinion. [PDF]
Ugwu OP, Ugwu CN, Anyanwu GE, Basajja M.
europepmc +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Optimization of multi-objective flexible scheduling for container rail mounted gantry cranes in railway logistics yards. [PDF]
Wang H, Xu C, Hou Y, Zhang J, Liu Z.
europepmc +1 more source
Usage of (returnable) containers for takeaway food
USAGE OF (RETURNABLE) CONTAINERS FOR TAKEAWAY FOOD Usage of (returnable) containers for takeaway food / Süßbauer, Elisabeth (Rights reserved) (-
Pade, Alexander +3 more
core
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source

