Results 171 to 180 of about 890,462 (337)

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Knowledge, attitudes and practice by health professionals toward medical and pharmaceutical waste management: a cross-sectional study of El-idrissi hospital, Kenitra, Morocco. [PDF]

Front Health Serv
Bouchama A, Chakit M, Mountaj N, Fritah K, Habsaoui A.   +4 more
europepmc   +1 more source

Now welcoming spill-proof containers [PDF]

, 2010
Lebed, Dana
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Autofluorescence and Fourier transform infrared analyses trace dietary fluorophores and reveal plastic contamination in the gut of mosquito larvae. [PDF]

Sci Rep
Soldano S, Weththimuni ML, Oldani A, Girella A, Moyano A, Croce AC, Licchelli M, Gomulski LM, Scolari F.   +8 more
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Habitat characteristics that favour the presence of Aedes aegypti (Diptera: Culicidae) in households in the city of Córdoba, a temperate area of Argentina. [PDF]

Parasit Vectors
Soria C, Crocco LB, Grech MG, Stewart-Ibarra A, Almirón WR.   +4 more
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Oral Bait Immunization of Eurasian Wild Boar (<i>Sus scrofa</i>) Against African Swine Fever with "ASFV-G-ΔI177L": Bait Performance, Immunogenicity, and Environmental Monitoring. [PDF]

Vaccines (Basel)
Beckmann J, Blome S, Bujan N, Gortázar C, Holzum T, Ortmann S, Relimpio D, Schäfer A, Viaplana E, Vos A, Friedrichs V.   +10 more
europepmc   +1 more source

Autonomic Vertical Elasticity of Docker Containers with ELASTICDOCKER

IEEE International Conference on Cloud Computing, 2017
Yahya Al-Dhuraibi, Fawaz Paraiso, N. Djarallah, Philippe Merle   +3 more
semanticscholar   +1 more source