Results 111 to 120 of about 2,268,554 (359)

A Mutual Contamination Analysis of Mixed Membership and Partial Label Models [PDF]

, 2016
Julian Katz-Samuels, Clayton Scott
openalex   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

The combination of polystyrene microplastics and di (2-ethylhexyl) phthalate promotes the conjugative transfer of antibiotic resistance genes between bacteria

Ecotoxicology and Environmental Safety
Plastic pollution has become a common phenomenon. The process of plastic degradation is accompanied by the release of microplastics and plasticizers.
Yu Li, Xiaomei Liu, Saisai Guo, Lan Wang, Jingchun Tang   +4 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

High damage potential of seed-borne spot blotch in organically grown spring barley in Denmark [PDF]

, 2005
Spot blotch of barley (Bipolaris sorokiniana, perfect state: Cochliobolus sativus) occurs wherever barley is grown but is normally not considered a major problem in Danish barley production.
Hansen, Henrik J., Nielsen, Bent J., Pinnschmidt, Hans O.   +2 more
core  

Ground-water, surface-water, and bottom-sediment contamination in the O-field area, Aberdeen Proving Ground, Maryland, and the possible effects of selected remedial actions on ground water [PDF]

, 1995
Don A. Vroblesky, Michelle M. Lorah, James P. Oliveros   +2 more
openalex   +1 more source

Special issue on “geochemistry, soil contamination and human health. Part 1” [PDF]

, 2021
Jaume Bech
openalex   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Spacelab contamination assessment. Payload/orbiter contamination control requirement study [PDF]

The activities and the results obtained under the payload/orbiter contamination control requirement study were documented, and the integrated shuttle payload contamination evaluation computer model was developed.
Bareiss, L. E., Hetdrick, M. A., Ress, E. B.   +2 more
core   +1 more source

MERCURY CONTAMINATION IN TOP SOIL AND SELECTED PLANT SPECIES IN AREA OF VEĽKÁ STUDŇA Hg-DEPOSIT (MALACHOV, SLOVAKIA) [PDF]

, 2018
High concentrations of mercury represent a big risk to the environment due to the high toxicity of this metal. One of anthropic sources of up-ground environmental mercury contamination is mining industry.
Midul, Pavol, Wiche, Oliver
core