Results 91 to 100 of about 1,280,182 (302)

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Sales Loss Determination in Food Contamination Incidents: An Application to Milk Bans in Hawaii [PDF]

This article presents a procedure for estimating sales loss following a food contamination incident with application to the case of heptachlor contamination of fresh fluid milk in Oahu, Hawaii in 1982. A major finding is that media coverage following the
Thompson, Stanley R., Smith, Mark E., van Ravenswaay, Eileen O.   +2 more
core  

Machine Learning Approach for Groundwater Contamination Spatiotemporal Relationship Exploration

Addressing groundwater contamination, this study applies machine learning (ML) algorithms to explore the spatiotemporal dynamics of hexavalent chromium (Cr[VI]) at the Hanford 100-Area.
Xuehang Song, Jayesh Soni, Leonel Lagos, Himanshu Upadhyay, Masudur Siddiquee   +4 more
core   +1 more source

Organic Contamination Distribution Constrained with Induced Polarization at a Waste Disposal Site

, 2022
Waste disposal sites are a serious concern due to their potential contamination threat. Site characterizations are the basis for contamination remediation, among which borehole-based methods are time-consuming.
Lili Guo, Chen Chao, Chunmei Han, Shupeng Li, Jian Meng, Deqiang Mao, Jiaming Zhang   +6 more
core   +1 more source

Effects of microplastics on microbial community and greenhouse gas emission in soil: A critical review

Ecotoxicology and Environmental Safety
Microplastics (MPs) are ubiquitous in soil ecosystems and significantly impact soil microorganisms and greenhouse gas (GHG) emissions. Although some reviews have summarized their impact on greenhouse gas emissions, no systematic analysis has been ...
Guanlin Chen, Saisai Guo, Linan Liu, Wenzhu Zhang, Jingchun Tang   +4 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Water Quality Indices: Current and Future Trends in Evaluating Contamination of Groundwater Resources

, 2021
Groundwater and surface water contamination is related to the presence of chemical substances, which strongly influence the water suitability for human consumption as well as for industrial and agricultural uses [...
Dimitrios E. Alexakis
core   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Modeling Land Subsidence Under Future Water Stress: The Influence of Groundwater Exploitation, Climate Change, and Inter‐Basin Water Diversion

Water Resources Research
Land subsidence driven by groundwater exploitation poses a critical threat under future water stress from population growth, urbanization, and economic expansion. While the relationship between groundwater level (GWL) fluctuations and land subsidence has
Hongkai Li, Zhilin Guo, Kewei Chen, Yang Zhan, Yushan Wang, Chen Ding, Chunhui Lu, Chunmiao Zheng   +7 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source