Results 81 to 90 of about 2,268,554 (359)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Robust nonparametric inference for the median

open access: yes, 2005
We consider the problem of constructing robust nonparametric confidence intervals and tests of hypothesis for the median when the data distribution is unknown and the data may contain a small fraction of contamination.
Yohai, Victor J., Zamar, Ruben H.
core   +1 more source

Cosmopatriot Contaminations

open access: yes, 2007
This article explores how Beijing Hip Hop collective Yin Tsang, visual artist Xu Bing and filmmaker Stephen Chow employ different tactics to negotiate between cosmopolitanism and patriotism. All are involved in a translation of a wide range of cultural forms, a translation that involves a betrayal and pollution of culture - be it music, language or ...
openaire   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Radiation-resistant Ti/BN coatings: insights from 171 days exposure to space radiation and atomic oxygen in low orbit

open access: yesnpj Materials Degradation
Atmospheric Plasma Spray (APS) and Vacuum Plasma Spray (VPS) techniques were used to develop Ti/2 vol.% hBN coatings, for extreme space environments and tested aboard the International Space Station as part of the MISSE-17 (Materials International Space ...
Abhijith Kunneparambil Sukumaran   +14 more
doaj   +1 more source

Characterization and modeling of contamination for Lyman break galaxy samples at high redshift [PDF]

open access: yes, 2017
The selection of high redshift sources from broad-band photometry using the Lyman-break galaxy (LBG) technique is a well established methodology, but the characterization of its contamination for the faintest sources is still incomplete.
Bouwens, Rychard   +6 more
core   +3 more sources

HEAVY METAL ACCUMULATION AND MIGRATION IN SOILS AND PLANTS UNDER CONTAMINATION IN URBAN ENVIRONMENTS

open access: diamond, 2022
Александр Сергеевич Петухов   +7 more
openalex   +2 more sources

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