Results 61 to 70 of about 2,268,554 (359)
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Anthropogenic Pb contribution in soils of Southeast China estimated by Pb isotopic ratios
Scientific Reports, 2020 Isotopic ratios were used to identify the source of Lead (Pb) contamination in rural soils from Southeast China. Enrichment of Pb in surface soils was detected from three sampling locations, with the 206Pb/207Pb ratio indicating recent anthropogenic ...
Jianwu Li +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Reducing Contamination in Forensic Science [PDF]
, 2015 The sensitivity of modern forensic techniques has drastically increased, with sensitive technology detecting even the smallest traces of DNA evidence left behind. This has made it possible to detect DNA profiles deposited through contamination.
Balk, Carly
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
AgronomyMagnesium plays a crucial role in plant physiological processes. However, the specific mechanisms underlying the response of tea plants to altered magnesium nutrition under acid stress remain unclear.
Xinhang Lv +8 more
doaj +1 more source
A Behavioral Test of Contamination Fear in Excessive Health Anxiety [PDF]
, 2012 Hypochondriasis and health anxiety are characterized by preoccupation with the fear of currently having a serious physical illness. The Diagnostic and Statistical Manual of Mental Disorders conceptualization of hypochondriasis does not include ...
Brady, Robert Edwin
core +2 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
International Journal of Bio-Resource and Stress Management, 2017 Spices can be considered as one of the sources of bacterial food pollution because of spices multiuse, in addition to the manufacturing processing and use, also they considered as one of food contamination reason due to the quantity of microorganisms ...
Ahmed Ibrahim Jessim +2 more
doaj