Results 51 to 60 of about 2,268,554 (359)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Effects of application of rice husk biochar and limestone on cadmium accumulation in wheat under glasshouse and field conditions

Scientific Reports, 2022
Cadmium (Cd) has seriously threatened the safe production of food crops. Passivator amendments are commonly used to control the soil Cd availability. Yet, few studies are tested to explore the effect of the combination of various amendments.
Zehui Niu, Jiayan Ma, Xianzhi Fang, Zhaokun Xue, Zhengqian Ye   +4 more
doaj   +1 more source

Advancement in utilization of magnetic catalysts for production of sustainable biofuels

Frontiers in Chemistry, 2023
In this study, we summarize recent advances in the synthesis of magnetic catalysts utilized for biodiesel production, particularly focusing on the physicochemical properties, activity, and reusability of magnetic mixed metal oxides, supported magnetic ...
Yutao Zhang, Yutao Zhang, Yutao Zhang, Weihua Li, Jialu Wang, Jiaxing Jin, Yixi Zhang, Jingsong Cheng, Qiuyun Zhang, Qiuyun Zhang, Qiuyun Zhang   +10 more
doaj   +1 more source

Random contamination and select response styles affecting measures of fit and reliability in factor analysis [PDF]

, 2017
This research examines the effects of nonattending response pattern contamination and select response style patterns on measures of model fit (CFI) and internal reliability (Cronbach's α). A simulation study examines the effects resulting from percentage
Harbaugh, A. G., Liu, Min
core  

Assessing depleted uranium (DU) contamination of soil, plants and earthworms at UK weapons testing sites [PDF]

, 2007
Depleted uranium (DU) weapons testing programmes have been conducted at two locations within the UK. An investigation was therefore carried out to assess the extent of any environmental contamination arising from these test programmes using both alpha ...
Angus B. MacKenzie, Bem, Boag, Bou-Rabee, Danesi, Danesi, Desideri, Di Lella, Di Lella, Ellam, Fisenne, Goldstein, Hamilton, Hu, Ian W. Oliver, Jia, Jia, John G. Farmer, Langdon, Magnoni, Margaret C. Graham, Robert M. Ellam, Rodriguez, Sansone, Sheppard, Sheppard, Tanaka, Trueman, Vera Tome, Yafa, Yamamoto, Yoshida   +31 more
core   +2 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Combined Effects of Microplastics and Biochar on the Removal of Polycyclic Aromatic Hydrocarbons and Phthalate Esters and Its Potential Microbial Ecological Mechanism

Frontiers in Microbiology, 2021
Microplastics (MPs) have been attracting wide attention. Biochar (BC) application could improve the soil quality in the contaminated soil. Currently, most studies focused on the effect of MPs or BC on the soil properties and microbial community, while ...
Xinwei Ren, Xinwei Ren, Xinwei Ren, Xinwei Ren, Jingchun Tang, Lan Wang, Hongwen Sun   +6 more
doaj   +1 more source

Comparing Cosmic Microwave Background Datasets [PDF]

, 1998
To extract reliable cosmic parameters from cosmic microwave background datasets, it is essential to show that the data are not contaminated by residual non-cosmological signals. We describe general statistical approaches to this problem, with an emphasis
A. de Oliveira-Costa, A. H. Jaffe, A. Kogut, B. Draine, C. A. Inman, C. B. Netterfield, C. H. Lineweaver, D. Charbonneau, D. J. Fixsen, D. J. Fixsen, E. J. Wollack, E. S. Cheng, E. S. Cheng, E. S. Cheng, G. Jungman, G. Jungman, J. E. Ruhl, J. Mather, J. R. Bond, J. R. Bond, J. R. Bond, J. R. Bond, K. Ganga, L. Knox, L. Knox, M. Segal, M. Tegmark, P. C. Gregory, Readhead, S. R. Platt, T. N. I. Gautier   +30 more
core   +2 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Coupling of Multi-Hydrochemical and Statistical Methods for Identifying Apparent Background Levels of Major Components in Shallow Groundwater in Shanghai, China

Hydrology
The determination of groundwater background levels is a prerequisite for assessing and analyzing groundwater characteristics. Shanghai is among the most economically developed regions in China and is located in the estuary of the Yangtze River, where ...
Qingqing Li, Min Ji, Shiyang Zhang, Jie Yang, Hainan Lu   +4 more
doaj   +1 more source