Results 71 to 80 of about 1,073,941 (318)

Validating the cleanliness of contamination-critical products

open access: yes, 2012
S.15-21Bei einer Vielzahl innovativer Produkte spielt die Kontrolle von Kontaminationen eine wesentliche Rolle. Trotz des Einsatzes angepasster Reinraumtechnik können dabei kritische Kontaminationen in der Massenproduktion nicht völlig ausgeschlossen ...
Kreck, Guido, Holzapfel, Yvonne
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Environmental contamination : a selection of papers presented at the 5th International Conference on Environmental Contamination, Morges, Switzerland, 29 September-1 October 1992 /

open access: yes, 1993
This book deals with various aspects of environmental contamination. One of the fields considered in this work is atmospheric pollution. This has become a major problem of our time, and could soon develop into a scandal through the overestimation of the ...
Vernet, J.-P.(Jean-Pierre)   +1 more
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Responses of nitrobenzene removal performance and microbial community by modified biochar supported zerovalent iron in anaerobic soil

open access: yesScientific Reports
Biochar-supported ZVI have received increasing attention for their potential to remove nitrobenzene in groundwater and soil. However, the capacity of this material to enhance the biological reduction of nitrobenzene and alter microbial communities in ...
Lu Hainan   +7 more
doaj   +1 more source

Remediation of Pb-, Zn-, Cu-, and Cd-Contaminated Soil in a Lead–Zinc Mining Area by Co-Cropping Ilex cornuta and Epipremnum aureum with Illite Application

open access: yesAgriculture
Phytoremediation is considered an effective strategy for remediation of heavy-metal-contaminated soil in mining areas. However, single-species plants cannot reach the highest potential for uptake of heavy metals due to inhibition of their growth by high ...
Qi Li   +9 more
doaj   +1 more source

Kinetic Study of Biodangerous Methylmercury Degradation under Various Light Conditions

open access: yesJournal of Chemistry, 2019
Methylmercury (MeHg) has remarkable toxicological effects on humans, plants, and other lives in the environment, which may restrict the comprehensive utilization of biomass source in view of possibly forming biohazardous waste.
Yutao Zhang   +4 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

The prevalence of bacterial contamination in donated blood in Dar es salaam, Tanzania [PDF]

open access: yes, 2012
Blood transfusion services are required to provide blood and components which are safe in cost effective way for transfusion into patients who require the blood products.
Malimu, Emmanuel Zephania, Zephania, M.E
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

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