Results 131 to 140 of about 2,241,681 (342)
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Microplastic inhibits the sorption of trichloroethylene on modified biochar
Water Science and TechnologyBiochar (BC) was used to remove trichloroethylene (TCE) from soil and water phases, and BC modification changed the sorption behavior of pollutants. Microplastics are emerging pollutants in the soil and water phases.
Hainan Lu
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Journal of FungiReducing the use of chemical inputs is becoming a major challenge in developing sustainable agriculture. Fungi, known as biocontrol agents (BCAs) and biofertilisers, are crucial in scientific research and are celebrated for their efficacy, eco ...
Ziqi Yuan +6 more
doaj +1 more source
Spacelab contamination assessment. Payload/orbiter contamination control requirement study [PDF]
The activities and the results obtained under the payload/orbiter contamination control requirement study were documented, and the integrated shuttle payload contamination evaluation computer model was developed.
Bareiss, L. E. +2 more
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Impact of oil contamination and biostimulation on the diversity of indigenous bacterial communities in soil microcosms [PDF]
, 2004 Flávia F. Evans +8 more
openalex +1 more source
Skylab atmospheric contamination control [PDF]
The Skylab contamination removal systems, preflight analysis and testing, and flight results are described. Results indicate that the combination of materials selection, the onboard removal devices, and the offgassing tests proved to be an effective ...
Ray, C. D.
core +1 more source
Risk management in organic coffee supply chains : testing the usefulness of critical risk models [PDF]
, 2011 This report documents the findings of the analysis of the supply chain of organic coffee from Uganda to the Netherlands using a Chain Risk Model (CRM). The CRM considers contamination of organic coffee with chemicals as a threat for the supply chain, and
Benninga, J. +2 more
core +1 more source