Results 41 to 50 of about 1,781 (263)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
‘Deconstructing Gao Minglu: critical reflections on contemporaneity and associated exceptionalist readings of contemporary Chinese art’ [PDF]
Journal of Art Historiography, 2014 In this article, I shall seek to offer an ethically/politically focused critique of exceptionalist accounts of the development of contemporary Chinese art.
Paul Gladston
doaj
Carnets, 2016 Rewinding time from « Délibération » (1979) to « La réponse de Kafka » (1960), this article aims to examine the tearing (déchirante) contemporaneity of Barthes through the secret dialogue he had with Kafka: one of his ways to get to « the truth of the ...
Emmanuel Bouju
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
The Relevance of St. Peter the Apostle's Theology in the Modern World
Studia ParadyskieA Theology, from its beginnings, has played a key role in shaping both the early Church and the development of emerging societies. It was a teaching that not only provided the foundations of faith and morals but also constituted the foundation of the ...
Piotr Borowski
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Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
То a problem of special terminology: the fine arts compound, a modern aesthetics
Освітній вимір, 2006 In the article analised the value of basic terms of fine art and their disparity to semantic maintenance of inlaind in them, and by similarly conducted the analysis of role and types of fine art in modern society.
D.A. Plyako
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Divination and contemporaneity
Inscriptions, 2023 This article compares two essential concepts: one is Schleiermacher’s divination, and another is Kierkegaard’s contemporaneity. These concepts cannot be understood without “religiousness”. The first part of this article presents a preliminary study on the convergence and divergence of Schleiermacher and Kierkegaard on religiousness.
openaire +1 more source