Results 91 to 100 of about 693,736 (295)

Content Based Document Recommender using Deep Learning

open access: yes, 2017
With the recent advancements in information technology there has been a huge surge in amount of data available. But information retrieval technology has not been able to keep up with this pace of information generation resulting in over spending of time ...
Nikhil, Nishant   +1 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

An Agent Framework of Tourism Recommender System

open access: yesMATEC Web of Conferences, 2016
This paper proposes the development of an Agent framework for tourism recommender system. The recommender system can be featured as an online web application which is capable of generating a personalized list of preference attractions for tourists ...
Jia Zhi Yang, Gao Wei, Shi Yi Jin
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Australian Governments and dilemmas in filtering the Internet: juggling freedoms against potential for harm [PDF]

open access: yes
This paper examines proposed internet filtering policies in Australia from the 1990s to 2014 and discusses some of their ideological underpinnings. Executive summary The Internet is a revolutionary source of information and its dissemination; and a ...
Paula Pyburne, Rhonda Jolly
core  

Unsupervised Visual and Textual Information Fusion in Multimedia Retrieval - A Graph-based Point of View [PDF]

open access: yes, 2014
Multimedia collections are more than ever growing in size and diversity. Effective multimedia retrieval systems are thus critical to access these datasets from the end-user perspective and in a scalable way.
Ah-Pine, Julien   +2 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Implementation of Content Based Filtering Algorithm in Comic Recommendation System

open access: yesSistemasi: Jurnal Sistem Informasi
Currently, the interest of comic readers in Indonesia is increasing and has become a popular culture. With so many comics released each year, it makes it difficult for the readers to find comics that fulfill their criteria, therefore the recommendation ...
Reyhan Alana, Adi Hartanto
doaj   +1 more source

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