Results 41 to 50 of about 230,040 (300)
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Interactive Content Based Image Retrieval using Multiuser Feedback
JOIV: International Journal on Informatics Visualization, 2017 Retrieving images from large databases becomes a difficult task. Content based image retrieval (CBIR) deals with retrieval of images based on their similarities in content (features) between the query image and the target image.
M. Premkumar, R. Sowmya
doaj +1 more source
Combined global and local semantic feature–based image retrieval analysis with interactive feedback
Measurement + Control, 2020 Nowadays, user expects image retrieval systems using a large database as an active research area for the investigators. Generally, content-based image retrieval system retrieves the images based on the low-level features, high-level features, or the ...
A Anandh, K Mala, R Suresh Babu
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
İçerik Tabanlı Görüntü Erişimi / Content-Based Image Retrieval
Bilgi Dünyası, 2005 Digital image collections are expanding day by day, and image retrieval becomes even harder. Both individuals and institutions encounter serious problems when building their image archives and later when retrieving the archived images. Visual information
İrem Soydal, Umut Al, Umut Sezen
doaj
Image Retrieval Berdasarkan Fitur Warna, Bentuk, dan Tekstur
ComTech, 2014 Along with the times, information retrieval is no longer just on textual data, but also the visual data. The technique was originally used is Text-Based Image Retrieval (TBIR), but the technique still has some shortcomings such as the relevance of the ...
Rita Layona +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Co-word mapping of Image Retrieval based on Web of Science-Indexed Papers [PDF]
مجله علمسنجی کاسپین, 2017 Background and aim: Given the special status and wide usage of image retrieval in various fields, the present investigation studied on the research trends and significant factors within the field of image retrieval and drawing the co-word map based on ...
Samira Daniali +2 more
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Correlated Primary Visual Texton Histogram Features for Content Base Image Retrieval
IEEE Access, 2018 In this paper, a new feature descriptor, named correlated primary visual texton histogram features (CPV-THF), for image retrieval is proposed. CPV-THF integrates the visual content and semantic information of the image by finding correlations among the ...
Ahmad Raza +5 more
doaj +1 more source