Results 41 to 50 of about 64,555 (258)

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Image Retrieval Berdasarkan Fitur Warna, Bentuk, dan Tekstur

ComTech, 2014
Along with the times, information retrieval is no longer just on textual data, but also the visual data. The technique was originally used is Text-Based Image Retrieval (TBIR), but the technique still has some shortcomings such as the relevance of the ...
Rita Layona, Yovita Tunardi, Dian Felita Tanoto   +2 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

İçerik Tabanlı Görüntü Erişimi / Content-Based Image Retrieval

Bilgi Dünyası, 2005
Digital image collections are expanding day by day, and image retrieval becomes even harder. Both individuals and institutions encounter serious problems when building their image archives and later when retrieving the archived images. Visual information
İrem Soydal, Umut Al, Umut Sezen
doaj  

Content-Based Image Retrieval System

Ubiquity, 2008
The term CBIR seems to have originated in 1992, when it was describe experiments into automatic retrieval of images from a database, based on the colors and shapes present. Since then, the term has been used to describe the process of retrieving desired images from a large collection on the basis of syntactical image features. The techniques, tools and
Murari Mohan Sardar, Krishnendu Basuli, Saptarshi Naskar   +2 more
openaire   +1 more source

Content Based Image Retrieval [PDF]

International Journal of Trend in Scientific Research and Development, 2019
The incremented desideratum of content based image retrieval system can be found in a number of different domains such as Data Mining, Edification, Medical Imaging, Malefaction Aversion, climate, Remote Sensing and Management of Globe Resources. Google's image search and photo album implements such as image search, Google's Picasa project applications ...
Dr. Aziz Makandar, Mrs. Rashmi Somshekhar, Miss. Nayan Jadav   +2 more
openaire   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Prosemantic Features for Content-Based Image Retrieval [PDF]

, 2011
The final publication is available at Springer via http://dx.doi.org/10.1007/978-3-642-18449-9_8 Revised Selected Papers of 7th International Workshop, AMR 2009, Madrid, Spain, September 24-25, 2009 We present here, an image description approach based on prosemantic features.
CIOCCA, GIANLUIGI, CUSANO, CLAUDIO, Santini, S, SCHETTINI, RAIMONDO   +3 more
openaire   +2 more sources