Results 71 to 80 of about 230,040 (300)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Content-Based Image Retrieval Research
Physics Procedia, 2011 AbstractWith the development of multimedia technology, the rapid increasing usage of large image database becomes possible. To carry out its management and retrieval, Content-Based Image Retrieval (CBIR) is an effective method. This paper shows the advantage of content-based image retrieval system, as well as key technologies.
Duan, Guoyong, Yang, Jing, Yang, Yilong
openaire +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
CONTENT-BASED IMAGE RETRIEVAL USING EXPRESSION SENSITIVITY BY FUZZY INFERENCE SYSTEM
Jurnal Ilmiah Kursor: Menuju Solusi Teknologi Informasi, 2015 Image retrieval can be divided into two types context-based and the content-based. Image retrieval based on the content refers to the image features such as color, texture, shape, semantics or sensations.
Sukmawati Nur Endah +2 more
doaj +1 more source
Unsupervised Visual Hashing with Semantic Assistant for Content-Based Image Retrieval
IEEE Transactions on Knowledge and Data Engineering, 2017 As an emerging technology to support scalable content-based image retrieval (CBIR), hashing has recently received great attention and became a very active research domain.
Lei Zhu +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Intelligent and Secure Content-Based Image Retrieval for Mobile Users
IEEE Access, 2019 With the tremendous growth of smart mobile devices, the Content-Based Image Retrieval (CBIR) becomes popular and has great market potentials. Secure image retrieval has attracted considerable interests recently due to users’ security concerns.
Fei Liu +4 more
semanticscholar +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source