Results 91 to 100 of about 4,501 (286)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
A Trusted Lightweight Communication Strategy for Flying Named Data Networking
Sensors, 2018 Flying Ad hoc Network (FANET) is a new resource-constrained breed and instantiation of Mobile Ad hoc Network (MANET) employing Unmanned Aerial Vehicles (UAVs) as communicating nodes.
Ezedin Barka +5 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Queueing Theoretic Models for Multiuser MISO Content-Centric Networks with SDMA, NOMA, OMA and Rate-Splitting Downlink [PDF]
, 2021 Ramkumar Raghu +2 more
openalex +1 more source
Distributed Consensus in Content Centric Networking
, 2023 We describe a method to achieve distributed consensus in a Content Centric Network using the PAXOS algorithm. Consensus is necessary, for example, if multiple writers wish to agree on the current version number of a CCNx name or if multiple distributed systems wish to elect a leader for fast transaction processing.
openaire +2 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
A Thorough Review of Security in Information-Centric Networking
IET Information SecurityThe rapid evolution of technology has revealed the limitations of host-centric or IP address–based networks. To overcome these limitations, a new communication paradigm has emerged: the information-centric networking (ICN), which focuses on content (data)
Ado Adamou Abba Ari +6 more
doaj +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Effect of User Mobility upon Trust Building among Autonomous Content Routers in an Information‐Centric Network [PDF]
, 2018 Jerzy Konorski, Jakub Grochowski
openalex +1 more source