Results 131 to 140 of about 6,321,849 (288)
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Security & Scalability of Content-Centric Networking [PDF]
, 2010 By suggesting radical changes to the current Internet, approaches to clean-slate architectures run the risk of introducing new opportunities for attacks. These attacks can range from new forms of denial-of-service to attacks against other users’ privacy.
Lauinger, Tobias
core
Dynamic cache size transfer scheme based on replacement rate in content centric networking
Tongxin xuebao, 2015 How to allocate an appropriate cache size to each router and efficiently utilize the finite storage resources poses challenges to the caching performance in CCN (content centric networking).On the basis of homogeneous cache allocation,a dynamic cache ...
EGuo-dong G +3 more
doaj +2 more sources
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
The explosive growth in multimedia data flow, cloud-based services, mobile apps, and IoT devices is changing the needs of today's network infrastructures.
Dr. Reagan Ricafort +1 more
core +1 more source
Revolutionizing Networking Paradigms: A Comprehensive Exploration of Information-Centric Networking (ICN), Content-Centric Networking(CCNx) and Named Data Networking (NDN) [PDF]
The evolution of networking paradigms has led to the emergence of Information-Centric Networking (ICN), Content-centric networking (CCNx), and Named Data Networking (NDN).
Hoggard, Ciana +4 more
core +1 more source
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
FEBS Letters, EarlyView.The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source