Results 111 to 120 of about 9,135,826 (275)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Web2Talkshow:Transforming Web Content into

, 2008
We propose a new browsing system called "Web2Talkshow". It transforms declarative-based web content into humorous dialogbased TV-program-like content that is presented through cartoon animation and synthesized speech. The system does this based
Tv-Program-Like Content Based, Akiyo Nadamoto   +1 more
core  

Enriching MPEG-7 user models with content metadata

, 2006
MPEG-7 is an XML-based standard that provides tools for creating rich and structured multimedia content metadata. However, only an extremely limited range of preferences can be specified for user models and multimedia content metadata created by other ...
Agius, HW, Harry Agius, Angelides, MC, Marios Angelides   +3 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

De uitdaging van grootschalige stelsel voor ketencommunicatie : over de betekenis van het vakgebied 'Keteninformatisering in de rechtstaat'

, 2011
Wij leiden vooral op in kleinschalig rationeel denken, of het nu wiskunde, informatiekunde, geneeskunde of rechtswetenschappen betreft. Grootschalige stelsels plaatsen ons daarom in de praktijk voor moeilijke uitdagingen, omdat onze -op rationele ...
Sub Content & Knowledge Engineering begr, Grijpink, Jan, Content and Knowledge Engineering, Grijpink, J.H.A.M.   +3 more
core  

Accademischer Frauenzimmer-Spiegel, Das ist Einige curieuse Liebes-Begebenheiten, So sich in der That auf einer wohlbekandten Sächsischen Universität vor einigen Jahren zugetragen / Ausgefertigt von Le Content

Le Content ist ein PseudonymAutopsie nach dem Ex. der ULB Sachsen-AnhaltVorlageform des Erscheinungsvermerks: Jm Jahr 1718.Frontispiz (Kupferst.
Le Content
core   +1 more source

Coupled/Uncoupled solutions of RANS equations using a Jacobian-free Newton-Krylov method

, 2013
Solutions of the coupled Reynolds-averaged Navier-Stokes (RANS) system discretized by mean of high accurate schemes up to the seventh-order accuracy are compared to uncoupled RANS simulations in term of accuracy and convergence rate.
CINNELLA, Paola, C. Content, P. Y. Outtier   +2 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source