Results 111 to 120 of about 4,844,764 (298)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Improving Access to Web Archives through Innovative Analysis of PDF Content [PDF]

open access: yes, 2013
This paper discusses improving access to web archives through innovative analysis of PDF content. The paper discusses the overall workflow and describes the tools used to extract document features.
Phillips, Mark Edward   +1 more
core   +2 more sources

Citation and Content Analysis of Journal of Health Management and Informatics in 2014-2016

open access: yesJournal of Health Management & Informatics, 2018
Background: The aim of citation and content analysis is to improve the quality of scientific productions, identify the authors’ trends, etc., and finally provide solutions to improve the present status. Therefore, the aim of this study was to determine
Reza Mohammadi   +5 more
doaj  

Exploratory Study of Evaluative Techniques Used in Regional Development Literature Reviews [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2018
Recent interdisciplinary body of literature has witnessed the appearance of a significant numberof studies dealing with the way in which researchers interact with their target audience.
Olesia Mihai
doaj  

Search engine content analysis

open access: yes, 2008
Search engines have forever changed the way people access and discover knowledge, allowing information about almost any subject to be quickly and easily retrieved within seconds.
King, John Douglas
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The Use of Qualitative Content Analysis in Case Study Research

open access: yesForum: Qualitative Social Research, 2006
This paper aims at exploring and discussing the possibilities of applying qualitative content analysis as a (text) interpretation method in case study research.
Florian Kohlbacher
doaj  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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